#MolecularBiology #CellBiology #Mechanobiology #Biogerontology #sflorg
https://www.sflorg.com/2026/03/mbio03262601.html
"We live in an academic culture increasingly defined by metrics that attempt to quantify academic worth but inevitably fail to capture its full substance. Measures such as the H-index cannot account for the intangible yet profound contributions scientists make to the intellectual lives and careers of one another. Catherine cared deeply about people and invested enormous energy in sharpening their thinking and the clarity of the way they expressed their ideas. She did so not quietly or passively, but through direct and often challenging discussions that pushed their science to become clearer, stronger, and more honest. While her research alone has left an indelible mark on our understanding of secretion pathways and organelle dynamics, it is an irony Catherine herself would have appreciated—given her lifelong fascination with numbers—that perhaps her most enduring influence lies in contributions that resist quantification, carried forward in the work, confidence, and clarity of thought of those she trained, challenged, and inspired."
From: "In memoriam: Catherine Rabouille".
https://rupress.org/jcb/article/225/4/e202508130/281671/In-memoriam-Catherine-Rabouille-1962-2025-In
🔧 Flexibly assembled: Proteasomes, the cells’ garbage cans, are assembled in different ways
A new study by University Potsdam and the #UniCologne shows that the assembly of the proteasome, a central component of cellular protein quality control, does not follow a rigid program but uses flexible pathways. This discovery challenges established views in research.
📰 https://www.nature.com/articles/s41467-026-70525-w
#uniköln #unicologne #Proteasome #ProteinResearch #CellBiology
RE: https://fediscience.org/@PLOSBiology/116283668972869123
I’m channeling @CellySally to declare the #PaperThemeTune for this paper (and highlight) is “Accidents Will Happen" by Elvis Costello.
It suggests that alternative splicing (+ other) events are just accidents on the way to making the real protein's transcript.
#CellBiology
Today's talk will be:
Isaac Wong (Dunn School, Oxford)
Mechanical Principles of Centrosome Assembly and Function
CTU 0.08/09 at 13.05