Better Technology For Liquid Cancer Biopsies. A new “lab on a spinning disc” can detect and speed the analysis of cancer markers that will help to revolutionize both diagnosis and management of malignant disease. #cancer #diagnosis #ev #vesicles #oncology
https://www.instagram.com/p/DUl8icojego/
Howard G. Smith MD, AM on Instagram: "Better Technology For Liquid Cancer Biopsies A new “lab on a spinning disc” can detect and speed the analysis of cancer Markers that will help to revolutionize both diagnosis and management of malignant disease. Bioengineers at Boston’s Mass General Hospital have developed a fully automated device named SpinEx that is capable of isolating and analyzing tiny particles in the blood known as extracellular vesicles, or EVs. These vesicles are released by tumor cells and carry molecular signals that reveal whether cancer is present and pinpoint the type and the quantity of that cancer Current extracellular vesicle analysis methods are slow, manual, and limited to measuring one marker at a time. SpinEx, in contrast, speeds the process by combining the multiple steps of plasma separation, EV enrichment, and protein labeling of a minuscule 150 microliters of blood onto a single spinning disc that completes the process automatically. Two samples can be run simultaneously. The resultant unique EV protein “fingerprints” accurately distinguish cancer from non-cancer samples and successfully identify five different cancer types. After further clinical testing, this SpinEx technology will support earlier cancer detection, improved tumor classification, and ongoing monitoring following therapy all from a simple blood draw. https://medicalxpress.com/news/2026-01-lab-disc-device-paves-automated.html https://www.nature.com/articles/s41551-025-01601-7 https://wefluidics.com/sys-nd/1349.html #cancer #diagnosis #ev #vesicles #oncology"

1 likes, 0 comments - drhowardsmithreports on February 10, 2026: "Better Technology For Liquid Cancer Biopsies A new “lab on a spinning disc” can detect and speed the analysis of cancer Markers that will help to revolutionize both diagnosis and management of malignant disease. Bioengineers at Boston’s Mass General Hospital have developed a fully automated device named SpinEx that is capable of isolating and analyzing tiny particles in the blood known as extracellular vesicles, or EVs. These vesicles are released by tumor cells and carry molecular signals that reveal whether cancer is present and pinpoint the type and the quantity of that cancer Current extracellular vesicle analysis methods are slow, manual, and limited to measuring one marker at a time. SpinEx, in contrast, speeds the process by combining the multiple steps of plasma separation, EV enrichment, and protein labeling of a minuscule 150 microliters of blood onto a single spinning disc that completes the process automatically. Two samples can be run simultaneously. The resultant unique EV protein “fingerprints” accurately distinguish cancer from non-cancer samples and successfully identify five different cancer types. After further clinical testing, this SpinEx technology will support earlier cancer detection, improved tumor classification, and ongoing monitoring following therapy all from a simple blood draw. https://medicalxpress.com/news/2026-01-lab-disc-device-paves-automated.html https://www.nature.com/articles/s41551-025-01601-7 https://wefluidics.com/sys-nd/1349.html #cancer #diagnosis #ev #vesicles #oncology".

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A new study describes a key #molecular mechanism that explains how #cells exchange information through #extracellular #vesicles (EVs), small particles with great therapeutic potential.
#MolecularBiology #sflorg
https://www.sflorg.com/2025/11/mbol11282501.html
Scientific Frontline

Potential for new regenerative, oncological or anti-inflammatory therapies

[フロンティア] 細胞内の運び役キネシン (Kinesin) の働きを超高精細CGで映像化 最新科学が解き明かした命のメカニズムを紹介
https://www.youtube.com/watch?v=yrvf8V_yLGA
#youtube_NHK #キネシン #kinesin #KIF #ダイニン #dynein #vesicles #微小管 #microtubules #cell #science
[フロンティア] 細胞内の運び役キネシン (Kinesin) の働きを超高精細CGで映像化 最新科学が解き明かした命のメカニズムを紹介 | NHK

■フロンティア公式サイトhttps://www.web.nhk/tv/an/frontiers/pl/series-tep-PM34JL2L14?cid=dchk-yt-2511-19タモリさんとノーベル賞科学者・山中伸弥さんのW司会でお届けしたNHKスペシャルの大好評シリーズ「人体III」。そのプレミアムドキュ...

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NASA finds Titan’s alien lakes may be creating primitive cells

Saturn’s moon Titan may be more alive with possibilities than we thought. New NASA research suggests that in Titan’s freezing methane and ethane lakes, simple molecules could naturally arrange themselves into vesicles—tiny bubble-like structures that mimic the first steps toward life. These compartments, born from splashing droplets and complex chemistry in Titan’s atmosphere, could act like primitive cell walls.

ScienceDaily

NASA Research Shows Path Toward Protocells on Titan

Cell-like compartments called vesicles could form naturally in the lakes of Saturn’s moon, based on our current knowledge of the moon’s atmosphere and chemistry.

➡️ https://science.nasa.gov/science-research/planetary-science/astrobiology/path-toward-protocells-on-titan/
➡️ https://doi.org/10.1017/S1473550425100037

#Titan #Saturn #astrobiology #Dragonfly #Life #cells #protocells #chemistry #science #news #astrodon #vesicles

NHKスペシャル「人体」細胞内の運び役キネシン(Kinesin)の働きを超高精細CGで映像化 最新科学が解き明かした命のメカニズムを紹介
https://www.youtube.com/watch?v=SpwaC_gvTV0
#youtube_NHK #NHK #NHKスペシャル #Nスペ #キネシン #kinesin #KIF #ダイニン #dynein #vesicles #微小管 #microtubules #cell #science #biology
NHKスペシャル「人体」細胞内の運び役キネシン(Kinesin)の働きを超高精細CGで映像化 最新科学が解き明かした命のメカニズムを紹介 | NHK

NHKスペシャル公式サイトhttps://www.nhk.jp/p/special/ts/2NY2QQLPM3/?cid=dchk-yt-2505-66タモリさんとノーベル賞科学者・山中伸弥さんのW司会でお届けする、大好評シリーズ「人体」。2025年4月から新シリーズ放送中!全4回、テーマは 「命とは何か」最新科...

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Gas #vesicles are hollow structures made of #protein found in the cells of certain #microorganisms, and researchers at Rice University believe they can be programmed for use in #biomedical applications.
#Microbiology #Biotechnology #Bioengineering #sflorg
https://www.sflorg.com/2024/03/mcb03292401.html
Rice study identifies protein responsible for gas vesicle clustering in bacteria

Finding could enable new synthetic biology applications

A coordinated recruitment of actin and myosin at large vesicles allows for the "exocytosis by vesicle crumpling" in Drosophila larval salivary glands.

Inès Jmel Boyer covers a preprint from Kumari Kamalesh & team which describes a mechanism that requires precise spatiotemporal control of actomyosin contractility.

#preLight 👉 https://prelights.biologists.com/highlights/structured-rhogef-recruitment-drives-myosin-ii-organization-on-large-exocytotic-vesicles-v2/

#CellBiology #CellMembrane #biomechanics #exocytosis #vesicles #actin #myosin

Structured RhoGEF recruitment drives myosin II organization on large exocytotic vesicles - preLights

A coordinated recruitment of actin and myosin at large vesicles allows for the "exocytosis by vesicle crumpling" in Drosophila Larval Salivary Glands

preLights
The researchers discovered that liver #cells have a clever way of compensating for the missing #enzyme. By clustering together and exchanging tiny, protein-wrapped packages called #vesicles, #liver cells are able to communicate and share the #biochemical materials needed to multiply, allowing them to proliferate even without #Shp2.
#Biology #Medical #sflorg
https://www.sflorg.com/2023/10/bio10172301.html
New Cancer Therapy Target Stops Tumor Cells From Sharing Resources

When times are tough, liver cells come together and share molecules needed to multiply; cancer cells may also do this to resist treatment

'Lava lamp' vesicles show how cells could self-organize

The inside of a living cell is crowded with large, complex molecules. New research on how these molecules could spontaneously organize themselves could further our understanding of how cells manage their essential biochemistry in the crowded space. This research may also shed light on how the first living systems appeared and how they evolved their complexities.

Phys.org