A coordinated recruitment of actin and myosin at large vesicles allows for the "exocytosis by vesicle crumpling" in Drosophila larval salivary glands.

Inès Jmel Boyer covers a preprint from Kumari Kamalesh & team which describes a mechanism that requires precise spatiotemporal control of actomyosin contractility.

#preLight 👉 https://prelights.biologists.com/highlights/structured-rhogef-recruitment-drives-myosin-ii-organization-on-large-exocytotic-vesicles-v2/

#CellBiology #CellMembrane #biomechanics #exocytosis #vesicles #actin #myosin