📰 "Kinesin Family Member 26A Disrupts DNA-Dependent Protein Kinase Complex Formation to Enhance Chemoradiotherapy Sensitivity in Colorectal Cancer"
https://doi.org/doi:10.7150/ijbs.127218https://pubmed.ncbi.nlm.nih.gov/42003912/ #KinesinKinesin Family Member 26A Disrupts DNA-Dependent Protein Kinase Complex Formation to Enhance Chemoradiotherapy Sensitivity in Colorectal Cancer
📰 "KIF18A Maintains Kinetochore-Microtubule Attachments in CIN Cells by Limiting Microtubule Polymerization"
https://www.biorxiv.org/content/10.64898/2026.04.15.718686v1?rss=1 #Microtubule #Kinesin📰 "KIF18A Maintains Kinetochore-Microtubule Attachments in CIN Cells by Limiting Microtubule Polymerization"
https://www.biorxiv.org/content/10.64898/2026.04.15.718686v1?rss=1 #Microtubule #Dynamics #Kinesin
Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch
Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects cargo recognition to motor activation.
Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch
Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects cargo recognition to motor activation.
📰 "KIF18B Modulates SKP2 Ubiquitination to Promote Aerobic Glycolysis and Osteosarcoma Progression"
https://doi.org/doi:10.3390/ijms27073235https://pubmed.ncbi.nlm.nih.gov/41977416/ #Kinesin📰 "RETRACTION: Kinesin Family Member 2A High Expression Correlates With Advanced Tumor Stages and Worse Prognosis in Non-Small Cell Lung Cancer Patients"
https://doi.org/doi:10.1002/jcla.70236https://pubmed.ncbi.nlm.nih.gov/41972894/ #Kinesin
Rxiv cytoskeleton
Rxiv mechanobio