Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.

#preLight prepared by Candy Rutihinda, R Bibata Ouédraogo and Bryce Rampal⬇️ 👀 #uMontreal
@umontreal.ca

https://prelights.biologists.com/highlights/molecular-interactome-of-hnrnpu-reveals-regulatory-networks-in-neuronal-differentiation-and-dna-methylation/

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation - preLights

Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.

preLights

Metastatic Matchmaking: CD24 Brings Tumour Cells and Platelets Together

Check out this excellent #preLight from Harvey Roweth, which includes answers and future directions from the authors of the preprint. ⬇️

https://prelights.biologists.com/highlights/tumoral-cd24-tunes-platelet-binding-and-pro-metastatic-functions/

#platelets #cancer #preprint #tumour

Tumoral CD24 tunes platelet binding and pro-metastatic functions - preLights

Metastatic Matchmaking: CD24 Brings Tumor Cells and Platelets Together

preLights

Using a forebrain assembloid model, Kim & team unveil that gene-regulating crosstalk between neurons & glial cells potentially contributes to developing schizophrenia. #preprint

#preLight prepared by Justine Gromaire, Aimee Xinxo & Jeremie Van Prooijen ⬇️ 👀 #uMontreal

https://prelights.biologists.com/highlights/identification-of-neuron-glia-signaling-feedback-in-human-schizophrenia-using-patient-derived-mix-and-match-forebrain-assembloids/

#neuroscience #assembloids #glia #neurons #schizophrenia

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids - preLights

Kim & team devise a forebrain assembloid model of schizophrenia to investigate the disease's complex etiology. Their model unveils that gene-regulating crosstalk between neurons and glial cells potentially contributes to developing schizophrenia.

preLights

Who “belongs” in biology?

The first comprehensive analysis of the LGBTQ+ climate in the biological sciences! #LGBTinSTEM #preprint 🏳️‍🌈

#preLight prepared by Ryan, Stefan & Reinier ⬇️ 👀
https://prelights.biologists.com/highlights/lgbtq-realities-in-the-biological-sciences/

#belonging #biology #community #inclusivity #LGBTQIA #survey

LGBTQ+ realities in the biological sciences - preLights

Who “belongs” in biology? Researchers conduct the first comprehensive analysis of the LGBTQ+ climate in biological sciences.

preLights

Swirl, align, invade!

Collective motion of cancer cells radially aligns collagen fibers and promotes invasion. #preprint Aashrith Saraswathibhatla et al. #theChaudhurilab

Check out the latest #preLight from Sharvari Pitke ⬇️ 👀

https://prelights.biologists.com/highlights/swirling-motion-of-breast-cancer-cells-radially-aligns-collagen-fibers-to-enable-collective-invasion/

#biology #cancer #CellMigration #metastasis #ECM

Swirling motion of breast cancer cells radially aligns collagen fibers to enable collective invasion - preLights

Swirl, align, invade! Collective motion of cancer cells radially aligns collagen fibers and promotes invasion.

preLights

‘These cracks, they let the developing cells in: A chronicle of trabeculation in the developing zebrafish heart’ 🎵

Theodora Stougiannou highlights recent work from Christopher Chan Jin Jie, Rashmi Priya & team. #preprint

Check out the #preLight ⬇️ 👀
https://prelights.biologists.com/highlights/mechanical-fracturing-of-the-extracellular-matrix-patterns-the-vertebrate-heart/

#DevBio #biology #heart

Mechanical fracturing of the extracellular matrix patterns the vertebrate heart - preLights

‘These cracks, They let the Developing Cells in: A Chronicle of Trabeculation in the developing Zebrafish Heart’ -- The authors of this study examine the initiating events that trigger trabecula formation in the zebrafish ventricle.

preLights

A new study from Washington State University explores the transgenerational impact of prenatal cannabis exposure in mice. #preprint

#preLight prepared by Behiye Sanliturk, Ali Gharbienne & Solal Aubailly ⬇️ 👀 #uMontreal

https://prelights.biologists.com/highlights/transgenerational-effects-of-perinatal-cannabis-exposure-on-female-reproductive-parameters-in-mice/

#neuroscience #pharmacology #toxicology

Transgenerational effects of perinatal cannabis exposure on female reproductive parameters in mice - preLights

We know cannabis use during pregnancy can cause developmental issues—but could those effects ripple through future generations? A new study from Washington State University explores the transgenerational impact of prenatal cannabis exposure in mice.

preLights

We can make decisions in our sleep! This #preprint reveals how the different sleep stages alter the underlying mechanisms of decision-making.

#preLight prepared by Joseph Lefèvre López & Nghi Vuong Nguyen ⬇️ 👀 #uMontreal

https://prelights.biologists.com/highlights/how-sleeping-minds-decide-state-specific-reconfigurations-of-lexical-decision-making/

#neuroscience #behaviour #cognition #decisionmaking

How sleeping minds decide: state-specific reconfigurations of lexical decision-making - preLights

We can make decisions in our sleep! This research reveals how the different sleep stages alter the underlying mechanisms of decision-making.

preLights

First preLights post from Jenny Singh!

She covers work showing that Lamin A/C maintains replication fork integrity during mild replication stress by modulating chromatin structure and restraining RECQ1 activity. #preprint

#preLight ⬇️👀
https://prelights.biologists.com/highlights/nucleoplasmic-lamin-a-c-controls-replication-fork-restart-upon-stress-by-modulating-local-h3k9me3-and-adp-ribosylation-levels/

#cancer #genetics #biology #chemotherapy #genome #nucleus

Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels - preLights

Lamin A/C maintains replication fork integrity during mild replication stress by modulating chromatin structure and restraining RECQ1 activity.

preLights

So many features…so little time: bumblebees show optimization of cue integration in a memory task. 🐝🐝

Really entertaining #preLight prepared by Tim Schwanitz & Cemre Coskun in which they highlight recent work from Anna Stöckl & team ⬇️ 👀

https://prelights.biologists.com/highlights/bumblebees-flexibly-adjust-learning-and-decision-strategies-to-sensory-information-content-in-a-foraging-task/

#behaviour #cognition #memory #neuroscience #bumblebees

Bumblebees flexibly adjust learning and decision strategies to sensory information content in a foraging task - preLights

so many features…so little time: bumblebees show optimization of cue integration in a memory task.

preLights