#RZZ-#Spindly complex and #CENPE (#kinesin-7) are intimately connected and reciprocally required for their own #kinetochore recruitment, #dynein/#dynactin localization, and expansion of the kinetochore fibrous corona
Verena Cmentowski @andreamusacchio et al
Happy #FluorescenceFriday!
This recent #preprint from the Reto Gassmann Lab (#i3S_UPorto) uncovers the role of the microtubule motor dynein in controlling the stem cell division axis in the developing C. elegans epidermis.
The figure below shows severely mis-oriented metaphase spindles in a hypomorphic dynein mutant.
Hello! A new intro for a new instance.
I lead a research group trying to figure out axonal transport and neurodegeneration. A big emphasis on the microtubules and their motors, but really the transport of anything that doesn't have a membrane around it. For this we use a lot of single molecule methods and live cell imaging. I also post about research culture.
#introduction #kinesin #dynein #microtubules #neurodegeneration #AxonalTransport #neurobiology #SingleMolecule #CellBiology
ATP-induced conformational change of #axonemal outer #dynein arms revealed by cryo-electron #tomography
#RefereedPreprint via @ReviewCommons by Takashi Ishikawa et al
NHK
Kirsty Wan
The EMBO Journal
preLights
Ali Twelvetrees
Anne Straube