📰 "Pathogenic MYBPC3 missense variants alter protein-protein interactions within the sarcomere"
https://www.biorxiv.org/content/10.64898/2026.05.27.727676v1?rss=1 #Myosin📰 "MYBPC1-associated congenital myopathy with tremor: further delineation of the clinical and pathological phenotype in the first Italian case"
https://doi.org/doi:10.3389/fgene.2026.1809063https://pubmed.ncbi.nlm.nih.gov/42211024/ #Myosin
Frontiers | MYBPC1-associated congenital myopathy with tremor: further delineation of the clinical and pathological phenotype in the first Italian case
The MYBPC1 gene, mapping to chromosome 12q23.2, encodes the slow myosin binding protein-C (sMyBP-C), a sarcomeric accessory protein, expressed mainly in slow...
📰 "Piezo1 links cytoskeletal remodeling to differential YAP and β-catenin signaling in response to mechanical cues"
https://www.biorxiv.org/content/10.64898/2026.05.28.728382v1?rss=1 #Myosin📰 "Modeling Hypertrophic Cardiomyopathy-Related MYH7 Variants: Insights into Structural Changes and Cardiovascular Drug-Binding Affinities"
https://doi.org/doi:10.1248/bpb.b26-00025https://pubmed.ncbi.nlm.nih.gov/42203436/ #MyosinModeling Hypertrophic Cardiomyopathy-Related MYH7 Variants: Insights into Structural Changes and Cardiovascular Drug-Binding Affinities
Mutations in the MYH7 gene, which encodes β-myosin heavy chain (β-MHC), are a significant cause of hypertrophic cardiomyopathy (HCM). These variants m …
📰 "Unresolved mechanisms: a hypothesized spatial regulation of myosin light chain phosphorylation within the walls of resistance arteries"
https://doi.org/doi:10.3389/fphys.2026.1816892https://pubmed.ncbi.nlm.nih.gov/42200182/ #Myosin
Frontiers | Unresolved mechanisms: a hypothesized spatial regulation of myosin light chain phosphorylation within the walls of resistance arteries
Myosin light chain (MLC) phosphorylation is a fundamental determinant of vascular smooth muscle contraction. While its biochemical regulation has been well-s...
📰 "Chamber-Specific Structural, Fibrotic, and Molecular Remodeling of the Heart in Experimental Metabolic Syndrome"
https://doi.org/doi:10.3390/ijms27104427https://pubmed.ncbi.nlm.nih.gov/42196399/ #Myosin📰 "Non-Syndromic or Anomaly-Associated Genes (MYH3, GREM1, IRF6) and Their Proteins in Unilateral Right Cleft Tissue"
https://doi.org/doi:10.3390/ijms27104158https://pubmed.ncbi.nlm.nih.gov/42196143/ #Myosin📰 "Changes in cardiac myosin acetylation disrupt the super-relaxed state in genotype-negative hypertrophic cardiomyopathy with type 2 diabetes"
https://doi.org/doi:10.1186/s12933-026-03211-2https://pubmed.ncbi.nlm.nih.gov/42192426/ #Myosin
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