Short-term #synaptic #plasticity (#STP) transiently modulates synaptic strength based on recent activity. #ShortTermDepression #STD reduces efficacy during repeated activity, while #ShortTermFacilitation #STF can enhance responses to closely spaced #spikes. These dynamics shape #NeuralProcessing, #filtering, and synaptic #homeostasis. Here's a short #Python implementation and simulation in #NESTSimulator:

🌍 https://www.fabriziomusacchio.com/blog/2026-05-25-std_and_stf/

#CompNeuro #Neuroscience #NeuralDynamics #TsodyksMarkramModel

RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

🧵1/2

Was ich bei Fedora so vermisse ist ein passabler GUI-Paketmanager wie Synaptic unter Debian/Ubuntu. Damit bin ich viele Jahre "groß geworden", seit dem Umstieg auf Fedora (KDE Plasma) vermisse ich das am meisten.

Discover finde ich mehr schlecht als recht, passt für Flatpaks und Updates aber sonst furchtbar.

Dnfdragora, das eigentlich Synaptic recht nahe kommt, funktioniert die halbe Zeit nicht - instabil ohne Ende, entweder lädt es die Liste gar nicht oder stürzt ab, mal früher mal später. Und wenn es mal funktioniert zeigt es mir nicht an was schon installiert ist und was nicht.
Selbiges auch wenn ich es aus der Quelle kompilliere. Damit wird es auch nicht besser. 🤷‍♂️

#Fedora #FedoraLinux #Paketmanager #Synaptic #Dnfdragora #Linux

@negativeprimes

IIRC some of Synaptic's dependencies are pretty archaic & Mint wants to get away from them.

When I installed Discover on Zorin & Mint, it was a simple matter of adjusting its settings to point to the OS's repos. 0 experience with Arch, but there are Arch-based distros (Garuda? Endeavour?) using KDE, so I presume there is a way to make it work

#KDE #LinuxMint #Synaptic

When synaptic #plasticity depends on more than spike timing alone, the #ClopathRule offers a biologically plausible model incorporating postsynaptic voltage dynamics. This voltage based #STDP model captures #synaptic change features such as frequency dependence and homeostatic stabilization making it useful for simulating #learning and #memory in #NeuralNetworks. Here's a brief introduction to that rule and its applications in #CompNeuro:

🌍 https://www.fabriziomusacchio.com/blog/2026-04-14-clopath_rule/

#Neuroscience

🧠 New publication from our lab 🥳! Nala ( @MaFu55 Lab, @dzne) & Naya (Corentin Le Magueresse Lab) show that #schizophrenia-associated complement C4 impairs #synaptic connectivity and alters #microglia–synapse interactions via #CR3 signaling.

📝 https://doi.org/10.1016/j.celrep.2026.117161

#Neuroscience 🧪 #2pImaging

Different setup for a bit due to home repairs, but the work continues.

New Roll Out just landed.

This week: an egg in every basket, how choice and flexibility build resilience in software and business.

Plus:
- Digital sovereignty
- Basket map exercise (1 main lane, 2 support lanes)
- It’s FOSS: Ubuntu hate, and a modern Synaptic-style package manager.

Read: https://rolandixor.pro/blog/post/the-roll-out-16

#adaptability #strategy #business #ubuntu #open-source #opensource #synaptic #debian #linux

Spike-timing-dependent #plasticity (#STDP) is a core rule in #ComputationalNeuroscience that adjusts #synaptic strength based on precise pre- vs. postsynaptic #spike timing, enabling #TemporalCoding and #learning in #SNN. In this post, I summarize its mathematical formulation, functional consequences for learning and #memory along with a simple #Python example:

🌍 https://www.fabriziomusacchio.com/blog/2026-02-12-stdp/

#CompNeuro #Neuroscience #SNN #NeuralDynamics #NeuralPlasticity