Mastodawn

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In this episode, Paul Middlebrooks talks with Cristopher Moore about the nature of computation and whether we should think of neural activity as computing.

https://www.thetransmitter.org/brain-inspired/are-computational-complexity-principles-relevant-for-explaining-brain-activity/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260617-bi-pod-christopher-moore

Fabrizio Musacchio 3d ago

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Mastodon 3d ago

A big new release after months of work is a good time to mention that #Mastodon is crowdfunded. Unlike many other platforms out there, we don’t take venture capital, we don’t sell ads, and we don’t sell your data. We rely on your donations to pay our team. Please consider chipping in:

https://joinmastodon.org/sponsors#donate

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Donate or become a sponsor and help us build the social web for everyone!

Fabrizio Musacchio 3d ago

Cleve Moler, #mathematician, cofounder of #MathWorks, and creator of #MATLAB, has died at 86. Say what you will about MATLAB, but its impact on #ScientificComputing is undeniable. As a student, I felt almost rebellious when I started coding in MATLAB instead of #Fortran 🤘

🌍 https://www.nytimes.com/2026/06/11/science/cleve-moler-dead.html

Fabrizio Musacchio 4d ago

🧠 What can a single neuron compute?

A new #bioRxiv #preprint introduces #TwinProp, using a differentiable digital twin to optimize synaptic strengths and locations in a detailed layer 5 #pyramidal #CellModel. One #neuron classified images and speech and even solved 10-bit parity with 91% accuracy. The key: distributed #dendritic nonlinearities, especially #NMDA-dependent integration:

📄 https://doi.org/10.64898/2026.06.08.730984

#CompNeuro #Neuroscience #Dendrites #NeuroAI @albertcardona https://mathstodon.xyz/@albertcardona/116764629463190653

Fabrizio Musacchio 4d ago

jordan, phd 5d ago

I never #tootprint'd my Contactomes paper, which is some of the science I am most proud of... so strap in :)

#academicchatter #preprint #neuroscience @kordinglab

Fabrizio Musacchio 4d ago

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jordan, phd 5d ago

Here's a beautiful shot of a single dendritic spine (black). It has ~3 synaptic partners (blue). But it has nearly TWENTY contact partners (red), which could be electrically or chemically influencing it! Made in #blender3d #blender @Blender

Fabrizio Musacchio 4d ago

Bernstein Network 5d ago

💬 Language processing: human brain and AI both work with predictions

This is the conclusion of a new study led by Bernstein member Patrick Krauss from @fau.de, among others.

Read the whole story 👉️ https://bit.ly/4eHr0kh

#BernsteinNetwork #CompNeuro #Neuroscience

Fabrizio Musacchio 5d ago

The #NEST Conference 2026 (https://nest-simulator.org/conference) has just started! I’m looking forward to two days of talks and discussions on #NeuralNetworks and the latest advances in the #NESTSimulator ✌️

Btw: We’re using #GatherTown again and I love creating these #8bit-like avatars there 👾

Fabrizio Musacchio 6d ago

I just pushed #OMIO to version v0.2.2. You can now reuse existing disk-backed #Zarr caches instead of rebuilding them every time an image is opened. OMIO stores cache metadata directly in the Zarr store and validates compatibility automatically before reuse ✌️

🌍 https://omio.readthedocs.io/en/latest/usage_large_files.html#reuse-an-existing-on-disk-omio-cache
👨‍💻 https://github.com/FabrizioMusacchio/omio

#Microscopy #BioimageAnalysis #Python #OpenScience

Website	https://www.fabriziomusacchio.com/
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