Fabrizio Musacchio

@FabMusacchio
724 Followers
206 Following
46 Posts

Physicist by training, working in computational neuroscience 🧠🔬💻 at the @dzne. Interested in how neural dynamics and learning shape brain function and behavior, using modeling and data analysis.

Modeling, science, open source, philosophy, photography. 🔍🚶🏻‍♂️

Previous posts are archived at @pixeltracker.
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Websitehttps://www.fabriziomusacchio.com/
GitHubhttps://github.com/FabrizioMusacchio
Blueskyhttps://bsky.app/profile/fabmusacchio.bsky.social

If you are interested in electron microscopy, registration is still open for the

"Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples"

at Stazione Zoologica in Naples.

WIth great teachers from Naples, Lausanne, EMBL and also our lab.

https://www.szn.it/index.php/en/education/advanced-courses-summer-schools/emhoc-2nd-edition-electron-microscopy-hands-on-course

#EM #microscopy #marine #imaging

Announcing the already-open applications for the 2026

Paris Spring School in Optical Imaging and Electrophysiological Recording in Neuroscience

http://parisneuro.ovh

Dates 11-23 May 2026

Application deadline 2 Feb.

Please boost, with apologies for duplicates.

Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

“Analysis of Biological Data with Python” started today for our biology bachelor students 🧬🐍

If you are interested in learning Python for data analysis, the course slides are freely available here:
https://github.com/bpucker/teaching/tree/master/WBIO-A-07

#Python #DataAnalysis #Biology #OpenEducation #OpenScience #Teaching #Bioinformatics #BigData #DataScience
@PuckerLab

If you'd like to study Computational Neuroscience in Berlin, don't miss this info event on Wednesday! 👉 https://www.bccn-berlin.de/events-list/information-day-2026-international-graduate-programs-computational-neuroscience.html #CompNeuro #BernsteinNetwork
Information Day 2026 - "International Graduate Program(s) Computational Neuroscience" - BCCN

When: January 14th, 2026, 15:00-18:00 CET Where: BCCN Berlin Lecture Hall (Philippstr. 12, Haus 6, 10115 Berlin) & Live-streamed via Zoom Registration: Registration will open in December 2026. Program: 15:00 - Virtual meeting opens 15:15 - Prof. Dr. Klaus Obermayer (head of the program) - What is Computational …

Is there a #mathematical framework for abrupt change? Christopher Zeeman was one of the key figures behind #CatastropheTheory, a topological approach to discontinuous behavior that later informed much of today’s work on #TippingPoints. Just came across his elegant 1976 paper, outlining his core ideas:

📄 https://www.jstor.org/stable/24950329

#DynamicalSystems #Topology #ComplexSystems

🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.

Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.

🌍 https://doi.org/10.7554/eLife.109538.1

#Neuroscience #CompNeuro #SynapticPlasticity

Very excited that our whole-mouse-brain analysis pipeline - DELiVR - is published now at Nature Methods. With DELiVR, we built an open-source, easy-to-use pipeline for analyzing image stacks from cleared mouse brains.

Paper: https://www.nature.com/articles/s41592-024-02245-2
Code: https://github.com/erturklab/delivr_cfos
Docker containers, test dataset, handbook: https://www.discotechnologies.org/DELiVR/

#neuroscience #tissueclearing #lightsheet #imageanalysis

Virtual reality-empowered deep-learning analysis of brain cells - Nature Methods

Generating training data for training deep-learning-based tools is time consuming. The DELiVR pipeline facilitates this process as demonstrated in this study on detecting c-Fos+ cells or microglia in the brain, following tissue clearing and imaging with light-sheet microscopy.

Nature

🧠 New preprint on adaptive contagion dynamics on #hypergraphs by Mancastroppa, Karsai, & Barrat.

The key result: adaptive, locally informed behavior can neutralize explosive phase transitions in higher-order contagion. Group-level awareness suppresses nonlinear reinforcement, shrinks bistability, and can turn a discontinuous transition into a continuous one. A nice mechanistic link between adaptivity, higher-order interactions, and phase transitions.

#ComplexSystems #NonlinearDynamics

🧬 New paper by Dera et al. in Science Advances proposing a geometric complexity space to map the full morphological diversity of life.

Striking result: life occupies only a tiny, clustered region of all geometrically possible forms, with large heteromorphic regions systematically avoided. The authors argue that this reflects deep physical and developmental constraints shaping evolution.

🌍 https://www.science.org/doi/10.1126/sciadv.aea6945

#Evolution #Complexity #Geometry #Morphology

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