🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.

Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.

🌍 https://doi.org/10.7554/eLife.109538.1

#Neuroscience #CompNeuro #SynapticPlasticity

#Synaptic...
СОБАКА...
КАК ЖЕ ОН #ХОРОШ
Не, конечно, довольно часто его глючит, видимо, потому, что в #репозиторий #KXAUDIO кто-то накидал несколько битых пакетов, но, да~~~ это #приложение сделало мне #вчера мой #день
Вот, не зря я, всё-таки, #Linux #Mint себе поставил - как только вошел в систему, так сразу эту репу подключил и всё, что мог, скачал
Теперь у меня супер-пупер-гига-мега-гипер-дупер сиджейский наборчик на Линуксе... Я СЧАСТЛИВ С БОЛЬШОЙ БУКВЫ "ЩА"...

#Synaptic is a PITA when you want to downgrade a package.
Try from the terminal:

sudo apt install <package name>=<version>

instead.

#linux #tech #ubuntu #debian #packages #conquerthecommandline #shell

🧠 New pre-print by Wiesner et al. (2025) shows non-#synaptic #exocytosis directly from the #axon shaft, regulated by the submembrane periodic skeleton. Using #superresolution #imaging and live assays (#HiLo (VAMP2-pHluorin), #SIM, and correlative two-color #SMLM/ #STORM) they reveal that #axons can release vesicles outside classical #synapses, expanding how we understand #neuronal communication and #AxonalSignaling.

🌍 https://doi.org/10.1101/2025.09.17.676728

#Neuroscience

Usage of #synaptic as a software center is a bit akward: first you have to enter the admin password and then it blocks apt because of that. But when I use /sbin/synaptic then it starts without #root privileges and I can browse packages without entering the admin password, it respects my dark theme and i can use apt install xxx at the same time (of course after entering the admin password). /sbin is not in the PATH variable, therefore synaptic alone ist not sufficient.

@mjaneai @v_raton 🇧🇷 O Gerenciador de Pacotes #Synaptic é brasileiro, sim, desenvolvido originalmente na saudosa Conectiva S/A. Eu ia indicá-lo, mas resolvi procurar antes se alguém já tinha citado. Sério que ninguém aí tinha o próprio para conferir? Não o troco. 🥰 

Segue a "prova do crime" então, diretamente do Debian GNU/Linux forky/sid.

#terSoftware #Debian #GNUlinux #Brasil #BrazilianSoftware #SoftwareLivre #GNU #FreeSoftware

#tersoftware de coisas brasileñas kkkkk

Vou trazer um aqui que usei a ins anos atrás no meu #Debian com XFCE e tenho suspeitas, sem privas concretas que ele foi a base pra o modelo de "App store" por pacotes que conhecemos hoje em dia

O #synaptic do Alfredo Kojima, na época da Conectiva....

Nessa época eu mal existia, mas anos depois tive o help dessa ferramenta e apenas apreciei, o quão complicado deveria ter sido o mundo linux antes dele.

https://wiki.debian.org/Synaptic

Synaptic - Debian Wiki

Conflicting results have been obtained re changes in synaptic strength in the #CerebralCortex during the #Sleep-WakeCycle. This computational study provides a comprehensive understanding & unified framework about #synaptic dynamics during #sleep & wake states @PLOSBiology https://plos.io/4kHeNwM
Liprin-α & RIM form presynaptic liquid phase-separated condensates #LLPS. This Primer explores a @PLOSBiology study of how these assemblies shape #synaptic fidelity and what their disruption might mean in #neurodevelopmental disease. Paper: https://plos.io/3Tj5CX7 Primer: https://plos.io/3HTacJ9
How do scaffolding proteins regulate the assembly of #presynaptic #ActiveZones? This study solves the structure of the liprin-α2/RIM1 complex & shows that it is essential for #synaptic transmission and LLPS-dependent coupling of Ca2+ channels & synaptic vesicles @PLOSBiology https://plos.io/3Tj5CX7