Meta-analysis of physical activity on the improvement of health-related quality of life among children and adolescents
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<b>Objective</b> To systematically review the effect of physical activity (PA) on health-related quality
of life (HRQoL) among children and adolescents and the magnitude of association, so
as to provide an evidence-based support for optimizing health promotion strategies
for children and adolescents.
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<b>Methods</b> Medline (PubMed), EMBASE, the Cochrane Library, SClELO, PEDro, CNKl, Wanfang and
VIP databases were searched to collect literature on PA and HRQoL in children and
adolescents, which were published up to January 1, 2025. Cochrane ROB tool and specific
evaluation system were used to assess literature quality, Stata 16.0 software was
used for Meta-analysis. For descriptive studies, correlation (
<i>r</i>) and 95% confidence interval (
<i>CI</i>) were used as effect indicators, and the inverse variance method was used to merge
the data. Standardized mean difference(
<i>SMD</i>) and 95%
<i>CI</i> were used to calculate the combined effect size of intervention studies.
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<b>Results</b> A total of 22 studies involving 27 303 healthy children and adolescents were included,
including 9 descriptive studies and 13 intervention studies. The results of descriptive
analysis showed that PA level was positively correlated with HRQoL (
<i>r</i> = 0.27, 95%
<i>CI</i> = 0.21-0.32,
<i>P</i><0.01). The analysis of intervention studies showed that PA had significant effects
on overall HRQoL (
<i>SMD</i> = 0.10, 95%
<i>CI</i> = 0.05-0.16), physical functioning (
<i>SMD</i> = 0.16, 95%
<i>CI</i> = 0.08-0.23), and mental functioning (
<i>SMD</i> = 0.17, 95%
<i>CI</i> = 0.10-0.25) (
<i>P</i><0.01). Subgroup analysis found that the effects of physical activity on overall HRQoL,
physiological function, and psychological function in children and adolescents were
maximized when the intervention duration was less than 6 months (
<i>SMD</i> = 0.13, 0.18, 0.20), the frequency was ≥5 times per week (
<i>SMD</i> = 0.13, 0.19, 0.24) and there was a supplementary plan (
<i>SMD</i> = 0.10, 0.18, 0.23)(
<i>P</i><0.01).
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<b>Conclusion</b> PA is an important factor affecting the HRQoL of healthy children and adolescents,
and the systematic PA intervention has a effect on improving the HRQoL.
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<b>【摘要】</b>
<b>目的</b>系统评价身体活动(PA)对儿童青少年健康相关生活质量(HRQoL)的影响及其关联程度, 为优化儿童青 少年健康促进策略提供循证依据。
<b>方法</b> 检索Medline (PubMed)、EMBASE、the Cochrane Library、SClELO、PEDro、中国知 网、万方和维普数据库, 收集建库至2025年1月1日关于儿童青少年PA与HRQoL的文献。根据Cochmne
ROB工具及特 定评价体系评估文献质量, Stata 16.0软件用于Meta分析。描述性研究采用相关值(
<i>r</i>)及95%置信区间(
<i>CI</i>)为效应指标, 借助倒方差法进行合并, 标准化均数差(
<i>SMD</i>)和95%
<i>CI</i>计算干预性研究的合并效应量。
<b>结果</b> 共纳入22篇文献(27 303 名健康儿童青少年), 包括9篇描述性研究和13篇干预性研究。描述性研究分析结果显示, PA水平与HRQoL呈正相关 (
<i>r</i> = 0.27,95%
<i>CI</i> =0.21〜0.32, 尸<0.01)。干预性研究分析表明, PA 对总体 HRQoL (
<i>SMD</i> = 0.10,95%
<i>CI</i> =0.05〜0.16)、生理功 能(
<i>SMD</i> = 0.16,95%
<i>CI</i> =0.08〜0.23)和心理功能(
<i>SMD</i> = 0.17,95%
<i>CI</i> = 0.10〜0.25)均有改善效果(
<i>P</i>值均<0.01)。亚组分析 发现, 身体活动对儿童青少年总体HRQoL、生理功能和心理功能方面的影响, 在干预时长<6个月(
<i>SMD</i>值分别为0.13, 0.18,0.20)、频率≥5次/周(
<i>SMD</i>值分别为0.13,0.19,0.24)、有补充方案(
<i>SMD</i>值分别为0.10,0.18,0.23)时达到改善效益 最大化(
<i>P</i>值均<0.01)。
<b>结论</b> PA是影响健康儿童青少年HRQoL的重要因素, 系统化的PA干预对提升HRQoL具有促进 作用。
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