Ruhrpott-PilzeCryptococcus luteus
#Cryptococcusluteus #Cryptococcus #Filobasidiellalutea #Filobasidiella #mushroom #mushrooms #fungus #fungi #pilz #pilze #champignons #champignon #nature #natur #FungiFriends
Cryptococcus luteus
#Cryptococcusluteus #Cryptococcus #Filobasidiellalutea #Filobasidiella #mushroom #mushrooms #fungus #fungi #pilz #pilze #champignons #champignon #nature #natur #FungiFriends
David OjciusButyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi
https://www.sciencedirect.com/science/article/abs/pii/S0092867425013716 #mycology #Candida #Cryptococcus
mymedschoolLearn key urease-positive organisms and their role in infection and diagnosis. #UreasePositive #Microbiology #Proteus #Klebsiella #HelicobacterPylori #StaphylococcusSaprophyticus #Ureaplasma #Nocardia #Cryptococcus #USMLE #MedicalEducation #ClinicalMicrobiology #BacterialMetabolism
Urease-Positive Organisms — Mechanism, Examples, and Diagnostic Importance
Discover the role of urease-positive organisms in disease pathogenesis and diagnosis. Learn how bacteria like Proteus, Klebsiella, H. pylori, and Staphylococcus saprophyticus use urease to survive hostile environments and cause infections.
PLOS BiologyEvolution of fungal mating systems: Study of #Cryptococcus & Kwoniella by @marcoacoelho1 &co shows that MAT locus fusions & recombination suppression drive diversity of #SexualReproduction in #fungi
@PLOSBiology plos.io/479579M
@PLOSBiology plos.io/479579M
#Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology https://plos.io/4dz3iVm
Alternative transcription start site (altTSS) usage in non-yeast #fungi: @vidang411 @guilhemjanbon &co reveal widespread altTSS in #Cryptococcus, altering gene expression & protein targeting, regulated by Tur1 in response to environmental cues #PLOSBiology https://plos.io/3A9RyJ6
Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1
Alternative transcription start site (altTSS) usage is one of the major means of gene regulation in animals but is unknown in non-yeast fungi. This study reveals widespread altTSS in Cryptococcus that alters gene expression and protein targeting, regulated by a single transcription factor, Tur1, in response to environmental cues.
Cosmin SaveanuA 6 months internship (M2) is open in our laboratory for January 2025 to work on #RNA, the genetics and biochemistry of its #splicing, export from the nucleus and degradation in the cytoplasm. With new tools and exciting preliminary results in #Cryptococcus neoformans, an intron-rich and fascinating human #fungal pathogen.
Do related pathogenic and non-pathogenic #fungi evolve differently? @MarcoACoelho1 @MrciaDavidPalm1 @DukeHeitman &co analyze #genomic evolution of #Cryptococcus & #Kwoniella, highlighting distinct mechanisms that drive diversity & lifestyles #PLOSBiology https://plos.io/3XfJXSW
Comparative genomics of the closely related fungal genera Cryptococcus and Kwoniella reveals karyotype dynamics and suggests evolutionary mechanisms of pathogenesis
Understanding the different evolution of closely related pathogenic and non-pathogenic fungi can help decipher the mechanisms of pathogenesis. In this study, comparative genomics is used to analyze the intricate genomic evolution of Cryptococcus and Kwoniella, highlighting distinct mechanisms that drive their biological diversity and lifestyles.
Gabriele PollaraPretty exciting to see oral amphotericin behaving comparably to IV amphotericin for #HIV associated #Cryptococcus #meningitis
Phase 2 open label #RCT, so not quite there yet, but big potential win in simplicity and access to treatment for
#Cryptococcusneoformans & other #fungal diseases, potentially even #mucor
#infectiousdiseases #mycology #IDMastodon #MedMastodon #medicine @infectiousdiseases
https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad440/7246927
