Comparative genomics of the closely related fungal genera Cryptococcus and Kwoniella reveals karyotype dynamics and suggests evolutionary mechanisms of pathogenesis

Understanding the different evolution of closely related pathogenic and non-pathogenic fungi can help decipher the mechanisms of pathogenesis. In this study, comparative genomics is used to analyze the intricate genomic evolution of Cryptococcus and Kwoniella, highlighting distinct mechanisms that drive their biological diversity and lifestyles.