Urease-Positive Organisms — Mechanism, Examples, and Diagnostic Importance

Discover the role of urease-positive organisms in disease pathogenesis and diagnosis. Learn how bacteria like Proteus, Klebsiella, H. pylori, and Staphylococcus saprophyticus use urease to survive hostile environments and cause infections.

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Chronic Granulomatous Disease (CGD) Pathophysiology: Catalase-Positive Infections Explained

Master the key features of chronic granulomatous disease (CGD) with this interactive drag-and-drop exercise. Learn why NADPH oxidase defects increase susceptibility to catalase-positive bacteria like Staphylococcus aureus and not Streptococcus. Ideal for USMLE Step 1 prep and clinical understanding.

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Sputum culture from a patient with bronchiectasis. #Nocardia is identified.
Sequence and structural analysis of NCY-1 demonstrate that it is a class A1 β-lactamase and show its very high conservation with those from other human-pathogenic Nocardia. @umontpellier #Nocardia #ClassABetaLactamases #BetaLactamResistance https://doi.org/10.1107/S2053230X23010671
Biochemical and structural characterization of a class A β-lactamase from Nocardia cyriacigeorgica

The crystal structure of a class A β-lactamase from a clinical strain of Nocardia cyriacigeorgica is reported at high resolution.

Acta Crystallographica Section F