🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?

🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics

Africa: Drug-Resistant Infections Rising Across Africa, Study Warns: [Premium Times] The African health organisation said that the study analysed more than 187,000 laboratory test results from 205 laboratories in 14 African countries, including Nigeria. http://newsfeed.facilit8.network/TQ8Cq5 #Africa #DrugResistance #HealthAwareness #Infections #PublicHealth
The Guardian view on antibiotics: recent breakthroughs are great news, but humanity is losing the bigger race

Editorial: Our magic bullets are increasingly rare and ineffective. The golden age of discovery is over and the way we develop and use drugs needs to change

The Guardian
New antibiotics hailed as ‘turning point’ in treating drug-resistant gonorrhoea

First new treatments for sexually transmitted disease in decades approved by US Food and Drug Administration as number of cases worldwide surge to 82m

The Guardian
Africa: Malaria - Drug Resistance and Underfunding Threaten Progress Towards Eliminating Killer Disease: [UN News] The authoritative World Health Organization (WHO) World Malaria Report, published on Thursday, shows that resistance to antimalarial drugs now poses one of the most acute risks to control efforts across Africa and beyond. http://newsfeed.facilit8.network/TPczhS #Malaria #DrugResistance #PublicHealth #WHO #AfricaHealth
Antibiotic resistance: how a pioneering trial is using old drugs to save babies from sepsis

The infection is responsible for 800,000 newborn deaths each year, but clinics in eight countries are working together to find new treatments

The Guardian
Africa: More Countries Report Rising Levels of Drug-Resistant Gonorrhoea, Warns WHO: [WHO] The World Health Organization (WHO) warns that gonorrhoea, a sexually transmitted infection, is becoming increasingly resistant to antibiotics, according to new data from its Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP), which monitors the spread of drug-resistant gonorrhoea. http://newsfeed.facilit8.network/TPLyTr #Gonorrhoea #DrugResistance #STI #WorldHealthOrganization #Antibiotics
New British initiative to use AI in the race to defeat drug-resistant "superbugs":
https://www.bbc.com/news/articles/cp97ggrnn35o
#AI #PublicHealth #DrugResistance #antibiotics #infection
Major AI project to tackle drug-resistant superbugs

The UK turns to artificial intelligence (AI) to reverse the rising numbers of infections that shrug off antibiotics.

🔬 Could a tiny imbalance in ATP binding be the key to drug resistance in cancer?

🔗 Nucleotide asymmetry and flexible linker dynamics modulate drug efflux cycle of P-glycoprotein, A computational study. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.064

📚 CSBJ: https://www.csbj.org/

#DrugResistance #MolecularDynamics #StructuralBiology #MembraneProteins #CancerResearch #Pharmacology #DrugDiscovery #ChemotherapyResistance #ProteinDynamics #Pgp #ABCB1 #Biophysics