Medikamente Zielsicher – Eine Elektrisch Gesteuerte Freisetzung
Vienna researchers developed a new way to control medicine release using electricity and click chemistry. This could make treatments more effective and reduce side effects.
#PrecisionMedicine, #DrugDelivery, #TUViennna, #MedicalResearch, #ClickChemistry
https://newsletter.tf/vienna-scientists-control-medicine-release-electricity/
This new technology allows doctors to control exactly when and where medicine is released, unlike older methods that sent medicine all over the body.
#PrecisionMedicine, #DrugDelivery, #TUViennna, #MedicalResearch, #ClickChemistry
https://newsletter.tf/vienna-scientists-control-medicine-release-electricity/
📢 Our latest work describing a new versatile click chemistry glycan linker which enabled us to create glycan derivatives for use in microarrays, Luminex (bead based arrays) and ELISA assays.
Check it out in @acs.org ACS Central Science https://doi.org/10.1021/acscentsci.4c02124
Check our new preprint !
Triple orthogonal labeling with 2 unnatural aminoacids + 1 SNAP-Tag for 3 color #smFRET.
We resolve a new intermediate in the activation of metabotropic glutamate receptor 2.
https://biorxiv.org/content/10.1101/2024.10.31.621373v1
Collaboration with Jean Philippe Pin & Philippe Rondard (IGF Montpellier) & Don Lamb (LMU Munich)
New ribozyme can make #RNA molecules accessible for #clickchemistry in living cells https://phys.org/news/2023-09-ribozyme-rna-molecules-accessible-click.html
Damn this is hot - imagine the possibilities for single sell #RNAseq @nanopore
#sequencing
RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, they enable biochemical reactions that would be difficult or impossible to occur on their own. These special RNA molecules that accelerate such reactions are called ribozymes.
Sahil Kamboj from our collaborator Ambroise Lambert’s lab showed us how @roylelab’s favourite tools can be used to develop probes to tackle key questions for understanding the #tumour microenvironment. The #clem + endocytosis hot-wiring in spheroids were amazing 🤩
It’s been a joy to follow my DTP colleague + friend Will Scott’s journey on using genetic code expansion + #clickchemistry to develop new tools for imaging #actin. I’m looking forward to seeing this probe in cells soon! #cellbiology
A new method to detect native #glycoRNA from Ryan Flynn's lab.
https://www.biorxiv.org/content/10.1101/2023.02.26.530106v1?med=mas
Nanotech Enzyme Process Boosts T-Cell Cancer Therapies
A #bioengineering team devised techniques for feasibly adding cancer-killing #enzymes to engineered #immune cells that in lab mice kill solid #tumor and blood #cancer cells.
https://sciencebusiness.technewslit.com/?p=44317
#News #Science #Engineering #Biotechnology #Chemistry #ClickChemistry #Nanotechnology #Cytokines #Preclinical #University
Sorry to the reviewer who chose an arbitrary out-of-subject field (chemistry) while trying to argue against the significance of my sister's paper. You couldn't have known we were related, but I got to squee at her about click chemistry for 10 minutes to describe why tool development is important for future discovery.
#SorryNotSorry #Science #ClickChemistry #ChemicalBiology #ChemiVerse
What a great, accessible summary of the work awarded the 2022 Nobel Prize in Chemistry (@[email protected], Meldal, Sharpless) by @[email protected] and @[email protected]!
https://www.nejm.org/doi/pdf/10.1056/NEJMcibr2213596?articleTools=true
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Gal Haimovich 😷🔬☣🏳️🌈🏳️⚧
Alan Kotok
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Freddy E Escorcia 
