One underlying cause of inflammatory bowel disease pinpointed in new study

Autoantibodies may be disabling one of the body’s anti-inflammatory brakes in some IBD patients, a new study finds.

#health #immune-system
https://www.livescience.com/health/immune-system/one-underlying-cause-of-inflammatory-bowel-disease-pinpointed-in-new-study

Men Can Lose Their Y Chromosome With Age, And We Finally Know The Cost : As some men age, they are losing the Y #chromosome in their blood, #brain , or #immune cells, and that could have serious health effects

https://www.sciencealert.com/men-can-lose-their-y-chromosome-with-age-and-we-finally-know-the-cost

Men Can Lose Their Y Chromosome With Age, And We Finally Know The Cost

The human Y chromosome is shrinking.

ScienceAlert
Fighting a cold? A meal gives your immune cells an immediate boost
Experiments in humans and mice suggest that certain white blood cells, known as T-cells, may respond to infections more effectively after a meal. The research calls into question the notion of "starve a fever, feed a cold."
https://www.cbc.ca/radio/quirks/diet-immune-system-9.7221119?cmp=rss
Host-associated microbiomes are stable across most of the lifespan, but what drives late-life deterioration remains unclear. @dvalenzano &co propose interventions that restore #immune surveillance capacity alongside ecologically informed #microbiome management.
#aging
https://doi.org/10.1371/journal.pbio.3003815
Immune surveillance and microbial escape in the aging host: Why does the microbiome lose its balance?

Host-associated microbiomes are stable across most of the lifespan, but what drives late-life deterioration remains unclear. This Unsolved Mystery proposes interventions that restore immune surveillance capacity alongside ecologically informed microbiome management.

@ufofeed genes that remained dysregulated were concentrated in #immune function, #DNA repair, #bone formation, hypoxia response, and mitochondrial activity. In other words, the cellular systems most stressed by #radiation and #microgravity were the ones that stayed altered the longest.
But #telomere became longer... but not for long after landing. #space
The GPR174 modulates #immune homeostasis by engaging distinct #Gproteins. This study shows that hydration-mediated interactions stabilize the active-state conformation of #GPR174 & reshape its intracellular cavity by enabling selectivity @PLOSBiology https://plos.io/4dsN81j
#Immune #cells in the peritoneal cavity can speed up the healing of distant skin #wounds – via fibronectin in the blood.🩸
New findings based on mouse and patient data from the Inselspital & #unibern open up ways to better predict impaired wound #healing 👇
https://sohub.io/vcxb
https://foreignpolicy.com/2026/04/14/trump-iran-bridges-power-plants-bombing-civilization-war-crimes/?tpcc=recirc_latest062921. This, of course, ignores the #Rome Statute, & any possible #action by the #International #Criminal #Court (ICC). The assumption is that the #US, its #Government, & all #agents of its government, are #immune from such action. That assumption will prove to be FALSE.
Understanding the Illegality of Trump’s Iran Threats

Destroying bridges and power plants would violate international law and expose service members to prosecution.

Foreign Policy

This review highlights the way #immune receptors and proteases work together to limit viral spread and reveals new opportunities to engineer #crops with stronger and broader resistance to #viral diseases.

https://doi.org/10.1111/jipb.70259
@WileyLifeSci
#PlantSci #JIPB #CropSci #PlantPath #botany