New paper by Maimon et al (Ulanovsky lab): recordings from #bats flying through tunnels up to 200 m reveal a sparse-to-dense transformation between #hippocampal #CA3 and #CA1.

In small environments, CA3 and CA1 #PlaceCells look similar. At large spatial scales, however, CA3 #neurons mostly show single, ultrasparse #PlaceFields, while CA1 neurons show dense multifield coding.

🌍 https://doi.org/10.1038/s41586-026-10537-0

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#Neuroscience #Hippocampus #SpatialNavigation #NeuralDynamics

🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

#Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

🌍 https://doi.org/10.1038/s41586-026-10528-1

#Neuroscience #CompNeuro #NeuralDynamics

🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior

Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.

🌍https://doi.org/10.64898/2026.01.03.696606

#NeuralDynamics

📚 New article by Esparza et al. and @LMPrida : Cell-type-specific #manifold analysis discloses independent parallel #SpatialMaps in #hippocampal #CA1. Using #miniscope imaging, they show deep and superficial CA1 #PyramidalNeurons encode position and running direction via distinct ring manifolds, manipulable via #chemogenetics. Fascinating for revealing parallel, cell-type–specific spatial topologies 👌

🌍 https://doi.org/10.1016/j.neuron.2025.01.022

#Neuroscience #CompNeuro

📚 New article by Lopes-dos-Santos, Brizee & Dupret: Spatio-temporal organization of network activity patterns in the #hippocampus. They use a low-dimensional embedding of #CA1–#DG #LFP in behaving mice to reveal layer-specific #GammaRhythms and distinct firing motifs aligned with hippocampal microcircuit architecture – offering a data-driven view of how #oscillations coordinate #InformationFlow across hippocampal layers.

🌍 https://doi.org/10.1016/j.celrep.2025.115808

#Neuroscience #GammaOscillations #CompNeuro

📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.

🌍 https://www.nature.com/articles/s41593-025-01986-3

#Hippocampus #Neuroscience