🧬 Can AI help researchers discover better proteins faster?

The Software Campus project ProtAl combines active learning and protein language models to explore new approaches for protein engineering—while putting transparency and usability at the center. 🚀🔬☁️

Participant: Sebastian Franz
Research Partners: @tu_muenchen / LMU Munich
Industry Partner: #Merck

Learn more via the link! 👇
https://softwarecampus.de/en/projekt/protal-an-active-learning-platform-for-protein-engineering/

#SoftwareCampus #Bioinformatics #ProteinEngineering #AI #Biotech

🤖 Have we built AI powerful enough to design proteins, but too complicated for most scientists to use?

🔗 BioPipelines: Accessible Computational Protein and Ligand Design for Chemical Biologists. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0129

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#BioPipelines #ProteinEngineering #ComputationalBiology #ProteinDesign #SyntheticBiology #Bioinformatics #AlphaFold #SystemsBiology #AI

🦠 Can a redesigned bacterial platform reshape the future of protein engineering?

🔗 Optimized Quantitative Bacterial Two-Hybrid (qB2H) for Protein–Protein Interaction Assessment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0098

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ProteinEngineering #SyntheticBiology #ProteinDesign #DrugDiscovery #ProteinInteractions #TherapeuticDiscovery

🦠 Could decoding bacterial regulatory proteins help us stay ahead of drug resistance?

🔗 Conserved Motifs in the Ligand-Binding Domain of TetR Family Regulators: Identification and Analysis. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0100

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Microbiology #MolecularBiology #Bioinformatics #AntimicrobialResistance #DrugDiscovery #ProteinEngineering #StructuralBiology #Genomics #ComputationalBiology

⚛️ Can spherical voxelization improve how AI interprets protein chemistry and interactions?

🔗 SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0076

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #Bioinformatics #ComputationalBiology #ProteinStructure #ArtificialIntelligence #ProteinEngineering #ProteinModeling

NTT Research Assistant Professor or Postdoctoral Scholar
Temple University

See the full job description on jobRxiv: https://jobrxiv.org/job/temple-university-27778-ntt-research-assistant-professor-or-postdoctoral-scholar/

#biochemistry #cellbiology #chemicalbiology #proteinengineering #Proteinexpressionandpurification #ScienceJobs #hiring #research
https://jobrxiv.org/job/temple-university-27778-ntt-research-assistant-professor-or-postdoctoral-scholar/?fsp_sid=11433

⚛️ Could life itself be a quantum phenomenon disguised as biology?

🔗 Quantum Biology Using Ultrafast Integrative and Molecular Engineering Tools: A Perspective. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0024

📚 CSBJ Quantum Biology and Biophotonics: https://spj.science.org/journal/csbj/qbio

#QuantumBiology #QuantumPhysics #MolecularBiology #ProteinEngineering #Biophysics #Biochemistry #Bioinformatics #SystemsBiology #MolecularDynamics #Lifesciences

NTT Research Assistant Professor or Postdoctoral Scholar
Temple University

See the full job description on jobRxiv: https://jobrxiv.org/job/temple-university-27778-ntt-research-assistant-professor-or-postdoctoral-scholar/

#biochemistry #cellbiology #chemicalbiology #proteinengineering #Proteinexpressionandpurification #ScienceJobs #hiring #research
https://jobrxiv.org/job/temple-university-27778-ntt-research-assistant-professor-or-postdoctoral-scholar/?fsp_sid=10761

Can the functions of #metalloenzymes be further improved using non-canonical amino acids?

In her talk at #Biochemistry2026, Alexandra Deliz Liang talked about the usage of genetic code expansion in order to improve the activity of metalloenzymes using e.g. hydrophobic tuning.

https://www.biorxiv.org/content/10.1101/2025.02.09.636911v1
#Chemistry #ChemBio #Biochemistry #BioinorganicChemistry #ProteinEngineering
CC: @gdch, @GDCh_BioChem

Alexandra Deliz Liang gave an exciting talk at #Biochemistry2026. She talked about her group's research on "Metalloenzyme engineering with genetic code expansion".

https://www.biorxiv.org/content/10.1101/2025.02.09.636911v1
#Biochemistry #Chemistry #ChemBio #ProteinEngineering #Metalloenzyme
CC: @gdch