🧬 Could a single residue swap turn a life-saving antibody into a “dead mutant”?

🔗 Replacement of a single residue in an antibody abolishes cognate antigen binding, as predicted by theoretical methods. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.018

📚 CSBJ: https://www.csbj.org/

#AntibodyEngineering #StructuralBiology #ComputationalBiology #ProteinModeling #Biophysics #Diagnostics #MolecularDynamics #MolecularSimulation #InfraredSpectroscopy #FTIR

🦟 Could smarter protein modeling unlock eco-friendly pest control?

🔗 TBM preferred to AlphaFold 3 for functional models of insect odorant receptors. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.028

📚 CSBJ: https://www.csbj.org/

#ComputationalBiology #StructuralBiology #Bioinformatics #ProteinModeling #AlphaFold #MolecularDocking #DrugDiscovery #InsectScience #AIinBiology #TransmembraneProteins

"Researchers glimpse the inner workings of #protein language models"

#AI #ProteinModeling #Science

https://news.mit.edu/2025/researchers-glimpse-inner-workings-protein-language-models-0818

✨ @SWISS_MODEL has a fresh new logo!

It evokes four globular chains of interacting proteins, as #SWISS-MODEL allows to model protein complexes in 3D. Discover this leading #ProteinStructure homology-modelling platform, one of the 14 leading Open Science bioinformatics resources developed by our teams to serve millions of scientists.

SIB provides support to enhance brand visibility of its resources alongside UX, data protection...

👉 Read more: https://www.sib.swiss/services/open-software-and-databases

#ProteinModeling