GDCh Division of Biochemistry"Dynamics of A-Minor Interactions in the Bacterial Ribosome"
Christian Steinmetzger talked at #Biochemistry2026 about his work on this topic in the group of Katja Petzold.
Stephan HackerHow can nature make #peptides covering chemical space beyond the 20 proteinogenic amino acids using the #ribosome?
Wilfred van der Donk talked at #Biochemistry2026 about the power of ribosomally-synthesized and post-translationally modified peptides #RiPPs.
https://pubs.rsc.org/en/content/articlelanding/2021/np/d0np00027b
#Biochemistry #Chemistry #ChemBio
Stephan HackerHow can nature make #peptides covering chemical space beyond the proteinogenic amino acids using the #ribosome?
Wilfred van der Donk talked at #Biochemistry2026 about the power of ribosomally-synthesized and post-translationally modified peptides #RiPPs.
pubs.rsc.org/en/content/a...
#Biochemistry
All ScientificalWhich ribosomal subunit does chloramphenicol target? π§«π #ribosome #chloramphenicol #pharmacology ... Continue to: https://www.youtube.com/watch?v=-SBl-bOO92M
Cytology and GeneticsLow Dose of Lead Causes Activation of Ribosomal Cistrons 15 Chromatids Associated with Malignant Growth - #leadions #ribosomalcistrons #chromatids15chromosomes #chromatidsassociation #PbCl2 #chromatid #ribosome #cistron - https://link.springer.com/article/10.3103/S0095452725050068
Low Dose of Lead Causes Activation of Ribosomal Cistrons 15 Chromatids Associated with Malignant Growth - Cytology and Genetics
Abstract Inactivation some regions of chromatin, heterochromatinization, can be caused by heavy metal lead. Normal blood levels of lead in children and adults are within the 0.1β0.2 ΞΌM range. Higher levels of 0.5β5 ΞΌM are known to have deleterious effects on digestive, respiratory, nervous, renal and reproductive tissues. The study results indicated that after induced with PbCl2 at a concentration of β 0.5 Γ 10β3 M and 0.5 Γ 10β4 M with 24β and 48 h of incubation in the human lymphocyte culture the number of chromosome aberration per cell, were significantly higher (results of heterochromatinization) than in the control group. Exposure to PbCl2 at a concentration of β 0.5 Γ 10β4 M during 24-h incubation indicated the activity of chromatids 15 chromosomes entering into associations (15 > 21 > 22 = 14 > 13) and the activity of chromatid in association of 15:15 chromosomes (15:15 > 13:13 = 14:14 = 21:21 = 22:22) increased significantly compared to the control (21 > 14 > 22 > 13 > 15) (p < 0.01 and p < 0.001, respectively). The results obtained indicate that low dose (0.5 Γ 10β4 M) of PbCl2 reveals the activity of 15 chromatids (characteristic for Breast and Lung cancer) than high mutagenic dose (0.5 Γ 10β3 M) when the activity of 15 chromatids is not observed. We suggest that the epigenetic activity of ribosomal cistrons of the 15 chromatid is associated with malignant growth. Our study of the activity of ribosomal cistrons of acrocentric chromatids in pathologies (Breast and Lung cancers, Down syndrome) is a new direction in medicine, indicating the contribute to the development of preventive, the diagnosis of diseases and defining a new treatment strategy in the future.
Andreas KalckerCOVID-19 mRNA "vaccines" are NOT vaccines
https://dioxitube.com/videos/watch/4054930f-0fdf-42cc-b255-f20131a95e67
COVID-19 mRNA "vaccines" are NOT vaccines
bert hubert πΊπ¦πͺπΊπΊπ¦Watch the majestic #ribosome it in action here. And unlike shitty human technology 3d printers, this one trivially prints copies of itself!
Keiran RowellStructure of an archaeal ribosome reveals a
divergent active site and hibernation factor | Nature Micro
"Ribosomes translate mRNA into protein. Despite divergence in ribosome structure over the course of evolution, the catalytic site, known as the peptidyl transferase centre (PTC) is thought to be nearly universally conserved. Here we identify clades of archaea that have highly divergent ribosomal RNA sequences in the PTC."
michaelI gather this is about reconstructing #ribosome #assembly in the #nucleolus - the PR is a bit wild but may be worth looking at the paper in Nature.
https://www.eurekalert.org/news-releases/1089618 #science #nanoworld #CellBiology #structuralBiology
CharrveinCool old study
Many Ribosomal Protein Genes Are Cancer Genes in Zebrafish
#zebrafish #ribosome #ribosomalProteins #zebrafish
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0020139
