I had agreed to this talk being recorded, because I learned so much from watching past editions of the #CCPEM Spring Symposium. This is stepping well out of my comfort zone, since public speaking isn't my strongest skill (by far). Anyway, here is the recording: https://www.youtube.com/watch?v=AKTfiUu720w

All other talks are in this playlist and are also well worth watching if you didn't attend in person or follow the live broadcast online!
https://www.youtube.com/playlist?list=PLo3ZBhRIiQ90kYfiTey_GYOgC-mLLfe02

#CryoEM

Atomic resolution structure of spinach rubisco reveals protons and dynamics | Guillaume Gaullier

YouTube
Postdoc Positions - Structural Biology, Biochemistry, Cell Biology

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
Molecular & Structural Biology Scientist (Internship to Hire)

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv

New Title Alert: CryoBoltz- is a method for fitting atomic structures into cryo-EM density maps of dynamic proteins. It is built on top of Boltz-1, a state-of-the-art structure prediction model for biomolecular complexes.

Learn more here: https://cryoboltz.cs.princeton.edu/

#SBGrid #Software #CryoEM

Cryoboltz

Multiscale guidance of protein structure prediction with heterogeneous cryo-EM data

RE: https://fediscience.org/@Guillawme/115798148618761432

This article on an ALC1-nucleosome complex with a new conformation was accepted at @ActaCrystD in April and went online today! Check it out!

https://doi.org/10.1107/S2059798326004158

#CryoEM #StructuralBiology #nucleosome #chromatin

Just found and #EMDB entry deposited in July 2020 without half-maps. 😮 I didn't know half-maps had been optional for so long...

#CryoEM

Postdoctoral Associate in Membrane Protein Structural Biology & Biophysics

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv

The next #CryoEM Current Practices Webinar speaker will be Biswanath Shaw from Cornell University speaking on "Navigating Cryo-EM Sample Preparation Challenges: Dock7 DHR2–Cdc42 Q61L Complex as a Case Study" 5/28/2026 at 12 PM ET / 9AM PT

Registration is at no-cost, but sign-up is required: https://us02web.zoom.us/webinar/register/WN_7qni6HVZTtmeBQoP0gHkbA#

RE: https://biologists.social/@biorxiv_molbio/116541272170828580

Nice preprint! Two new things:

1. A user-friendly workflow for low-dose data collection setup in SerialEM. Very nice to have an "easy mode" for SerialEM. 🙏

2. An atomic resolution #cryoEM structure of apoferritin at ~1.1 Å, with a R&H B-factor *3-fold* improved compared to the atomic res ApoF structures from 2020. 🤯 🤩
EMD-57470 and EMPIAR-13508

I am really puzzled why the first result defined the paper, and not the second one, but it's impressive either way!

RE: https://biologists.social/@biorxiv_biochem/116556723014784898

Very interesting to see that it is the same "difficult" particles that trip up classification methods with completely different underlying formalism. Also great to now have a #cryoEM dataset with known ground truth assignments!