Loss of nsp14-exonuclease activity impairs the #replication, proofreading, fitness, and #pathogenesis of #SARS-CoV-2, https://etidiohnew.blogspot.com/2026/05/loss-of-nsp14-exonuclease-activity.html
Loss of nsp14-exonuclease activity impairs the #replication, proofreading, fitness, and #pathogenesis of #SARS-CoV-2

How can research findings be made more durable over time?

A Nature analysis highlights key strategies to improve reproducibility, replicability, and robustness across the social and behavioural sciences.

🔗 https://www.nature.com/articles/d41586-026-00965-3

#OpenScience #Reproducibility #Replication #ResearchIntegrity #metascience

More self-reflection in research can lead to better science

A package of papers looking at the social and behavioural sciences shows the value of researchers collaborating to further the cause of reproducible, replicable and robust findings.

Opposing #cell type preferences for binding and #replication shape #influenza A virus infection in #human #airways

Transaction logs serve as the replication source in distributed databases. The primary node writes changes to its log; replica nodes consume those entries to stay synchronized, enabling high availability without data loss.

#WAL #Replication #DistributedSystems

#Niclosamide Inhibits the #Replication of Highly Pathogenic Avian #Influenza #H5Nx Viruses and Antiviral-Resistant #Mutants

PaperCall.io

#Replication Efficiency of Contemporary Highly Pathogenic Avian #Influenza #H5N1 Virus Isolates in #Human #Nasal Epithelium Model, https://etidiohnew.blogspot.com/2026/05/replication-efficiency-of-contemporary.html
#Replication Efficiency of Contemporary Highly Pathogenic Avian #Influenza #H5N1 Virus Isolates in #Human #Nasal Epithelium Model

A quorum system is a collection of sets — called quorums — where every two sets intersect. This intersection property ensures any two operations share at least one common node.

#Quorum #Replication #Fintech

Setelah kenalan sama litestream buat replikasi sqlite ke s3, sekarang giliran penjajakan sama "wal-g" buat nge-archive file wal database termasuk postgres.

wal-g/wal-g: Archival and Restoration for databases in the Cloud

https://github.com/wal-g/wal-g

#walg #postgres #postgresql #replication #s3 #litestream #sqlite #walfile

New large scale registered replication project probing Construal-Level Theory.
It shows the typical pattern: Hundreds of published studies (with positive effects), but virtually no replication attempts. Metaanalytic bias correction suggests true effect close to zero.

The preregistered replication:

* N = 11,775 from 27 countries and regions; 99.995% power for g = 0.23
* direct and paradigmatic replications

Results (positive effects are consistent with hypotheses):

* temporal, d = 0.08, 95% confidence interval [CI] = [0.003, 0.16] (effect in original study: d = 0.92);
* spatial, d = 0.04, 95% CI = [−0.03, 0.11] (effect in original study: d = 0.55);
* social, d = −0.27, 95% CI = [−0.34, −0.19]; and
* likelihood, d = 0.03, 95% CI = [−0.05, 0.11].

"These findings provide limited evidence for the predictions of the theory and present a critical challenge for CLT.“

OA paper: Calderon et al:: https://journals.sagepub.com/doi/full/10.1177/25152459251401177

#PsychScience #Replication #OpenScience https://getmona.app/rich_text/593518390090