#statstab #467 Replication, statistical consistency, and publication bias

Thoughts: Is the replication of a a finding the "gold standard" for scientific discovery? Maybe not.

#replication #metascience #metapsychology #statistics #bias #QRPs #nhst

https://doi.org/10.1016/j.jmp.2013.02.003

Is synchronous replication really slow—or a silver bullet for zero data loss? 🤔 Alexander Kukushkin breaks down myths vs. reality, sharing real-world tests and trade-offs of PostgreSQL synchronous replication. Learn when and how to use it right.

▶️ Watch now! https://www.youtube.com/watch?v=axkIoqxQzNQ&list=PL_m-TUcr7ZvnSBmPoxZvcB1lfy7C9eced&index=8

#PostgreSQL #PGDay #PPDD #Replication #HighAvailability

#Bovine-derived #influenza A virus #H5N1 shows efficient #replication in well-differentiated #human #nasal epithelial cells without requiring genetic #adaptation, https://etidiohnew.blogspot.com/2026/01/bovine-derived-influenza-virus-h5n1.html
#Bovine-derived #influenza A virus #H5N1 shows efficient #replication in well-differentiated #human #nasal epithelial cells without requiring genetic #adaptation

#throwback How does multi-master PostgreSQL really perform under pressure? 🔁 Alfredo Rodriguez shares a real-world case study using pgEdge/spock, stress-testing millions of transactions, conflicts, latency, and failover scenarios.

▶️ Watch the talk now! https://www.youtube.com/watch?v=79ueF49PI9s&list=PL_m-TUcr7ZvnSBmPoxZvcB1lfy7C9eced

#PostgreSQL #PGDay #PPDD #Replication #DatabaseEngineering

A new experiment asked 158 researchers in 71 teams to analyse the same #data and answer the same question: does immigration affect support for welfare policies? The results were all over the place - from strongly negative to strongly positive:

 https://doi.org/10.1126/sciadv.adz7173

The key finding: researchers’ political views mattered. Pro-immigration teams were more likely to find positive effects, while anti-immigration teams found negative ones.

#Ideology #OpenScience #Replication #Metascience

Today's #Januread was from

Isaac Asimov: Zweite Foundation
[Second Foundation, translated by Rosemarie Hundertmarck]

"You will soon experience having your calculations rigorously examined by five different boards and being required to defend them against a combined and merciless attack. Two years later, your contribution will be re-examined."

#Reading #Lesen #ScienceFiction #Replication

Januread by the #ScottishBookTrust supports reading every day in January:
https://www.scottishbooktrust.com/reading-and-stories/januread

Januread

Form the habit of a lifetime. Challenge yourself to read every day of January 2026, with Januread!

Scottish Book Trust
Giới thiệu pg-status — microservice nhẹ giúp kiểm tra trạng thái PostgreSQL host, xác định master và replica đồng bộ, hỗ trợ failover và cân bằng tải. Dễ triển khai dạng sidecar, viết bằng C, hiệu năng cao (1500 RPS), API đơn giản qua HTTP. Hỗ trợ đo độ trễ theo thời gian/bytes, tích hợp với libpq hoặc proxy. Phù hợp cho hệ thống cần độ tin cậy cao và phản ứng nhanh với sự cố. #PostgreSQL #Database #DevOps #Microservice #C #HighAvailability #pgstatus #sidecar #replication #failover #trạng_thái_C
Enhanced #genome #replication activity of pandemic #H1N1 #influenza A virus through PA #mutations

AI-Developed Strategy Blocks Viral Cell Entry. Bioengineers and virologists at Washington State University have uncovered an “on-off” switch that can completely block viral intrusion and reproduction. #ai #virus #infection #replication #fusion
https://www.instagram.com/p/DSlE_wzjQyN/
Howard G. Smith MD, AM on Instagram: "AI-Developed Strategy Blocks Viral Cell Entry Utilizing artificial intelligence to help discover the very nature of the process by which viruses enter human cells, bioengineers and virologists at Washington State University have uncovered an “on-off” switch that can completely block viral intrusion. Their study, published in the journal Nanoscale, focused on herpes viruses which utilize a “fusion” protein to enter human and animal cells. The researchers combined AI-driven analysis, high-resolution molecular simulations, and lab experiments to sift through thousands of protein interactions to pinpoint the single amino acid that is the regulator for herpesvirus entry. When this amino acid was altered, the herpesvirus could not fuse with or enter cells. This eliminates infection with viral reproduction before it even begins. We don’t know if this on-off switch is universal or herpesvirus-specific. It is, though, a powerful demonstration that machine learning can search a large body of biologic processes to find unique solutions to therapeutic problems…..someday soon. https://www.sciencedaily.com/releases/2025/12/251215084155.htm https://pubs.rsc.org/en/content/articlelanding/2025/nr/d5nr03235k #ai #virus #infection #replication #fusion"

Washington State University researchers utilized artificial intelligence to uncover an on-off switch that blocks herpesvirus entry into human cells. Their study, published in Nanoscale, combined AI-driven analysis, high-resolution molecular simulations, and lab experiments to identify a single amino acid responsible for herpesvirus entry. This breakthrough has the potential to find unique solutions to therapeutic problems and demonstrates the power of machine learning in biologic processes. #herpesvirus #viralcellentry #artificialintelligence #machinelearning #herpes #virology #infection #replication #fusion #onoffswitch #therapeutics #biologicprocesses #research

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