Giuseppe Michieli6d ago
Enhanced #genome #replication activity of pandemic #H1N1 #influenza A virus through PA #mutations, https://etidiohnew.blogspot.com/2025/12/enhanced-genome-replication-activity-of.html
Enhanced #genome #replication activity of pandemic #H1N1 #influenza A virus through PA #mutations

Howard Smith MD, AMDec 22
AI-Developed Strategy Blocks Viral Cell Entry. Bioengineers and virologists at Washington State University have uncovered an “on-off” switch that can completely block viral intrusion and reproduction. #ai #virus #infection #replication #fusion
https://www.instagram.com/p/DSlE_wzjQyN/
Howard G. Smith MD, AM on Instagram: "AI-Developed Strategy Blocks Viral Cell Entry Utilizing artificial intelligence to help discover the very nature of the process by which viruses enter human cells, bioengineers and virologists at Washington State University have uncovered an “on-off” switch that can completely block viral intrusion. Their study, published in the journal Nanoscale, focused on herpes viruses which utilize a “fusion” protein to enter human and animal cells. The researchers combined AI-driven analysis, high-resolution molecular simulations, and lab experiments to sift through thousands of protein interactions to pinpoint the single amino acid that is the regulator for herpesvirus entry. When this amino acid was altered, the herpesvirus could not fuse with or enter cells. This eliminates infection with viral reproduction before it even begins. We don’t know if this on-off switch is universal or herpesvirus-specific. It is, though, a powerful demonstration that machine learning can search a large body of biologic processes to find unique solutions to therapeutic problems…..someday soon. https://www.sciencedaily.com/releases/2025/12/251215084155.htm https://pubs.rsc.org/en/content/articlelanding/2025/nr/d5nr03235k #ai #virus #infection #replication #fusion"

Washington State University researchers utilized artificial intelligence to uncover an on-off switch that blocks herpesvirus entry into human cells. Their study, published in Nanoscale, combined AI-driven analysis, high-resolution molecular simulations, and lab experiments to identify a single amino acid responsible for herpesvirus entry. This breakthrough has the potential to find unique solutions to therapeutic problems and demonstrates the power of machine learning in biologic processes. #herpesvirus #viralcellentry #artificialintelligence #machinelearning #herpes #virology #infection #replication #fusion #onoffswitch #therapeutics #biologicprocesses #research

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Giuseppe MichieliDec 20
#Replication and #Transmission of #Influenza A Virus in Farmed #Mink, https://etidiohnew.blogspot.com/2025/12/replication-and-transmission-of.html
#Replication and #Transmission of #Influenza A Virus in Farmed #Mink

Giuseppe MichieliDec 19
Attachment and #replication of clade 2.3.4.4b #influenza #H5N1 viruses in #human respiratory #epithelium: an in-vitro study, https://etidiohnew.blogspot.com/2025/12/attachment-and-replication-of-clade.html
Attachment and #replication of clade 2.3.4.4b #influenza #H5N1 viruses in #human respiratory #epithelium: an in-vitro study

Michael DornerDec 17

Why do we seemingly all agree replication studies are essential for our discipline, yet make them so hard to publish? Where and how exactly can I publish a #softwareengineering replication study without being rejected for “lack of novelty” or accused of self-plagiarism?

#replication #research @seresearchers

Hacker NewsDec 15

DNA Learning Center: Mechanism of Replication 3D Animation

https://dnalc.cshl.edu/resources/3d/04-mechanism-of-replication-advanced.html

#HackerNews #DNA #Learning #Center #Mechanism #of #Replication #3D #Animation #Education #Science #Animation #Genetics

3D Animations - Replication: Mechanism of Replication (Advanced) - CSHL DNA Learning Center

3D Animations - Replication: Mechanism of Replication (Advanced)

Johannes BreuerDec 5
New paper by @drfollowmario, Philipp Knöpfle, and me in the journal Media Psychology: "Contextual Changes, Credible Conclusions? A Direct and Conceptual Replication of Shen et al.'s (2019) Study on Online Image Credibility"
https://www.tandfonline.com/doi/full/10.1080/15213269.2025.2595452
#commodon #replication #reproducibility @communicationscholars
Elen Le Foll 🇫🇷 🇬🇧 🇩🇪Nov 28
Today was my second time participating in the #Replication Games, this time in Münster, and this time with a 100% linguistics team, all from Cologne! 💪 Our team brought together a B.A. and M.A. student, two doctoral and one postdoctoral researcher, Marie Klünter, Rose Hörsting, Luca Leppert, Gina Reinhard, and myself. We worked hard to make sense of a fascinating but complex #linguistics paper with some 8 studies and several multi-study analyses, making for a lot of data and #Rstats scripts! 📉📈
Serhii NazarovetsNov 23

A new article by Chloe Patton shows how debates about #OpenScience often slip into absurdity – like demanding #replication from the #Humanities. You can’t replicate history, culture, or interpretation the way you replicate a physics experiment. It’s a different kind of knowledge.

 https://doi.org/10.1093/reseval/rvaf052

Forcing STEM-style standards onto the humanities doesn’t improve #science – it just adds bureaucracy and limits academic freedom.

#Reproducibility #ResearchEvaluation #Replicability

renebekkersNov 9
Here's a reasonable request: please provide access to the data and code producing the results reported in your manuscript, so that it will not go down the gutter as unverifiable magic.
Yet another study - this one by @ianhussey - finds that few authors claiming data are available upon request actually make them available upon request.
https://conferences.lnu.se/index.php/metapsychology/article/view/4008
#data #transparency #openscience #replication #reliability
LnuOpen | Meta-Psychology