A #Virtual #Cell is a comprehensive #Computational #Model that simulates the biological functions, physical interactions, and chemical processes of a living cell.

These models are used by researchers to predict how cells respond to drugs, genetic mutations, or environmental changes without needing to perform every experiment in a physical laboratory.

https://knowledgezone.co.in/kbits/69ba6c79dfdb802fae9eb527

MetaGenesis Core — Proof, Not Trust

Any computational result packaged into a tamper-evident evidence bundle. One command. PASS or FAIL. No trust required.

MetaGenesis Core
Caira Camera Reins In Its Built-In Generative AI After Blowback

After blowback, Camera Intelligence is dialing the built-in generative editing in its Caira Camera way back.

PetaPixel
Ah yes, the riveting tale of Python's GIL: the most misunderstood three-letter acronym since 'LOL' 😂. The authors propose unlocking #Python #cores as though they're disarming a bomb - spoiler alert: it's #energy, not nuclear 💥. Thank goodness we have 2603.04782 pages of #academic #wisdom to light our path through the dark forest of #computational #efficiency 🌳🔦.
https://arxiv.org/abs/2603.04782 #GIL #HackerNews #ngated
Unlocking Python's Cores: Hardware Usage and Energy Implications of Removing the GIL

Python's Global Interpreter Lock prevents execution on more than one CPU core at the same time, even when multiple threads are used. However, starting with Python 3.13 an experimental build allows disabling the GIL. While prior work has examined speedup implications of this disabling, the effects on energy consumption and hardware utilization have received less attention. This study measures execution time, CPU utilization, memory usage, and energy consumption using four workload categories: NumPy-based, sequential kernels, threaded numerical workloads, and threaded object workloads, comparing GIL and free-threaded builds of Python 3.14.2. The results highlight a trade-off. For parallelizable workloads operating on independent data, the free-threaded build reduces execution time by up to 4 times, with a proportional reduction in energy consumption, and effective multi-core utilization, at the cost of an increase in memory usage. In contrast, sequential workloads do not benefit from removing the GIL and instead show a 13-43% increase in energy consumption. Similarly, workloads where threads frequently access and modify the same objects show reduced improvements or even degradation due to lock contention. Across all workloads, energy consumption is proportional to execution time, indicating that disabling the GIL does not significantly affect power consumption, even when CPU utilization increases. When it comes to memory, the no-GIL build shows a general increase, more visible in virtual memory than in physical memory. This increase is primarily attributed to per-object locking, additional thread-safety mechanisms in the runtime, and the adoption of a new memory allocator. These findings suggest that Python's no-GIL build is not a universal improvement. Developers should evaluate whether their workload can effectively benefit from parallel execution before adoption.

arXiv.org

The Coordinated Action “Diagnostic, Therapeutic and Vaccine Viral Targets” of #ANRS MIE is organising a #webinar on #AI for molecular discovery. This webinar will explore how AI and #computational #modelling are advancing #drugdesign and protein research.
Speakers will present approaches for molecular design, prediction of protein variant effects and dynamics, and structural modelling of protein–protein interactions. The session will also take a critical perspective, addressing current limitations in #cheminformatics and practical considerations for researchers.

🚨 MARK YOUR CALENDAR 🚨
⚠️ AI for molecular discovery: From drug design to protein dynamics⚠️
April 15th 2026
12:30 - 14:00
Wednesday April 15th 2026, from 12:30 to 14:00 — online (Zoom)

Programme :

1️⃣ "AI for drug design" — Dragos Horvath, Strasbourg University
2️⃣ "Computational approaches for protein variant effect and motion prediction" — Elodie Laine, Sorbonne University
3️⃣ "Structural modelling and binding affinity prediction of the Human PDZ-PBM interactome" — Victor Reys, Utrecht University

➡️ Registration : https://services.hosting.augure.com/Response/c7juk/%7B6f9b7a92-f72c-4db8-9259-d92aaa0f0cc3%7D

Webinar Registration "AI for Molecular Discovery: From Drug Design to Protein Dynamics" - CA Viral Targets ANRS MIE

From 20-22 July, the 4th #ACM #Conference on Reproducibility and Replicability will take place in #Delft.
The conference welcomes contributions on methods, tools, case studies, and community efforts around #reproducibility and #replicability in #computational research.

Deadlines: 10 March (abstracts)/17 March (papers)

https://acm-rep.github.io/2026/cfp/

Foto by ThisIsEngineering on unsplash

A #computational modeling tool that incorporates #space debris collision probability directly into the earliest design phases of Earth-observation #satellite missions.
#Engineering #Spacecrafts #AerospaceEngineering #Astrodynamics #SpaceSustainability #sflorg
https://www.sflorg.com/2026/02/eng02162601.html
New tool could reduce collision risk for Earth-observation satellites

Earth-observation satellites are increasingly relied upon to support efforts to meet the United Nations’ 17 Sustainable Development Goals

@cathill
1. "The best camera is the one you have in your hand".
2. For some subjects a small #sensor is better than one as large as a DSLR and although there are nice little digital #camera sensors (my G11 still gets use) and they may have better lenses, a good pocket terminal may be not inferior.
3. The connected devices and network are good at #computational photography, where calculation makes up, or perhaps more than makes up, for optical deficiencies

My 6D is a reduction from the 10x8" ;)

A new #computational framework establishes a benchmark for determining the three-dimensional positions and elemental identities of individual #atoms within amorphous, disordered materials like glass.
#Nanotechnology #MaterialScience #Physics #sflorg
https://www.sflorg.com/2026/01/nt01282601.html
UCLA study sets new benchmarks for 3D, atom-by-atom maps of disordered materials

The team used algorithms to analyze rigorously simulated imaging data of nanoparticles

This guy here... this is a guy. I love this guy 🩷🧸🍷

How do you keep your little gooses on path? 🪿🦮

We're calling it Looking Glass Development. It's what happens when TDD and BDD have a wee bit too much wine when they're over for a visit with your teddy and what comes out has a wee bit more computational markdown in it than anyone wants to admit.

🧸🤷🏻‍♀️

You guys are already doing that thing where you use your user guide as the spec right?

Just add your unit tests at the bottom.

Living markdown.

🔴 ➡️ 🟢 ➡️ 🔄
♥️ 🏹 💚 🏹 🫶🏻

If the guide is accurate enough to direct accurate usage and the tests are passing then the garden has been well tended. 🌱

#ai #platform #living-documentation #computational-markdown