๐Ÿงช Daily Lab Note

Protein Myths Busted: What Science Really Says About Recovery
May 10, 2026 | Lab Notes

ยท New research suggests protein supplements aid recovery mainly through added calories, not protein alone
ยท Pre-exercise meals can change how effective post-workout carbohydrates are
ยท Science is rethinking common recovery nutrition strategies

#ProteinScience #RecoveryNutrition #FitnessMyths

https://s.fitbodyscience.com/zKeWDu

๐Ÿงฉ Could RNA and proteins share the same โ€œshape languageโ€ for binding drugs?

๐Ÿ”— Eigenvalue Ratios Reveal Shared Binding Pocket Shapes in RNA and Protein Structures. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0022

๐Ÿ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#DrugDiscovery #StructuralBiology #ComputationalBiology #RNAResearch #ProteinScience #Bioinformatics #MolecularModeling #Genomics #Proteomics #Cheminformatics #LigandBinding

๐Ÿฆด Could a naturally occurring โ€œbiological lubricantโ€ redefine how we treat joint health and gout?

๐Ÿ”— Lubricinโ€™s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021

๐Ÿ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

๐Ÿงฉ What if the diverse functions of a single protein all trace back to one structural superfamily?

๐Ÿ”— Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.003

๐Ÿ“š CSBJ: https://www.csbj.org/

#StructuralBiology #ComputationalBiology #MolecularEvolution #ProteinScience #Genomics #Proteomics #AlphaFold #MembraneProteins #Genetics #Bioinformatics

๐Ÿ’ช Could one molecular โ€œtypoโ€ break the balance between strength and flexibility in our muscles?

๐Ÿ”— Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.02.010

๐Ÿ“š CSBJ: https://www.csbj.org/

#ComputationalBiology #MolecularDynamics #ProteinScience #Actin #RareDiseases #PrecisionMedicine #Biophysics #CryoEM #Bioinformatics #DrugDiscovery #VisceralMyopathy #AorticAneurysm

๐Ÿงฌ Can we turn evolutionary signatures into maps of protein function?

๐Ÿ”— Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.012

๐Ÿ“š CSBJ: https://www.csbj.org/

#ProteinScience #StructuralBiology #ProteoSync #ComputationalBiology #Bioinformatics #EvolutionaryBiology #MolecularBiology #PyMOL

๐Ÿชจ Can sand-like molecules help us map the secrets of protein structure?

๐Ÿ”— Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic molecular dynamics simulations. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.004

๐Ÿ“š CSBJ: https://www.csbj.org/

#AtomProbeTomography #MolecularDynamics #Biophysics #ProteinStructure #Nanotech #ComputationalBiology #StructuralBiology #Biomaterials #ProteinScience

โš›๏ธ Have proteins evolved to operate at a quantum sweet spot between conduction and insulation?

๐Ÿ”— Holographic nature of critical quantum states of proteins. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.049

๐Ÿ“š CSBJ Quantum Biology and Biophotonics: https://www.csbj.org/qbio

#QuantumBiology #ProteinScience #Biophysics #AndersonTransition #Holography #Bioelectronics #Nanotechnology

๐Ÿ› ๏ธ Is it possible to rewire cellular energy control by targeting a single protein domain?

๐Ÿ”— Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.007

๐Ÿ“š CSBJ: https://www.csbj.org/

#Mitochondria #CellBiology #CalciumSignaling #ProteinEngineering #ProteinScience #StructuralBiology #Bioenergetics #MolecularDynamics #Biophysics #MCU #MCUb #NMR

This study introduces plmCP, an innovative method for detecting circular permutations (CPs) in proteins using Protein Language Models (PLMs)โ€”paving the way for deeper insights into protein evolution, engineering, and synthetic biology.

๐Ÿ”— Detection of circular permutations by Protein Language Models. Computational and Structural Biotech Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.029

๐Ÿ“š CSBJ: https://www.csbj.org/

#ProteinScience #AIinBiotech #SyntheticBiology #Bioinformatics #ProteinEngineering