Rich WaldoI need you to know that every time you invite me to give an introductory #cryoEM talk I think to myself, "*this* time I'll make the sample irradiation animation I see in my dreams"
PLOS BiologyThe human G6P transporter (G6PT) translocates G6P into the #ER. This study solves hi-res #cryoEM structures of #G6PT in both outward-open & dimeric states, providing insights into the mechanistic basis for G6P substrate recognition & transport cycle @PLOSBiology https://plos.io/4m15UQ5
Stephan HackerHe also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (7/7)
#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin
Stephan HackerHe also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (8/8)
#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin
Guillaume GaullierHere is a strong candidate for the coolest-looking #cryoEM structure of 2026! 🤩
Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
Ed EngThe next #CryoEM Current Practices Webinar speaker will be by Rashmi Panigrahi from Memorial University of Newfoundland, St. John’s, Canada speaking on "Capturing Chromatin Dynamics During the DNA Damage Response" 3/26/2026 at 12 PM ET / 9AM PT
Registration is at no-cost, but sign-up is required: https://us02web.zoom.us/webinar/register/WN_NAkOLFAAT7eNeSt49yOYBg
jobRxivPostdoctoral Associate in Membrane Protein Structural Biology & Biophysics
Duke University School of Medicine
See the full job description on jobRxiv: https://jobrxiv.org/job/duke-university-school-of-medicine-27778-postdoctoral-associate-in-membrane-protein-structural-biology-biophysics/
#cellularbiophysics #cryoEM #ionchannels #membranep...
https://jobrxiv.org/job/duke-university-school-of-medicine-27778-postdoctoral-associate-in-membrane-protein-structural-biology-biophysics/?fsp_sid=10553
GDCh Division of BiochemistryIn the final talk of #Biochemistry2026, Stefan Raunser gave an exciting overview of his group's research on "Unlocking the secrets of the cytoskeleton and heart muscle".
https://www.annualreviews.org/content/journals/10.1146/annurev-biochem-052521-042909
#Biochemistry #Chemistry #ChemBio #Structure #cryoEM
CC @gdch
How do our muscles work on a molecular scale?
Stefan Raunser gave an inspiring lecture on his group's work at the Max Planck Institute of Molecular Physiology, in which they elucidate this question with a great combination of biochemistry and structural biology.
https://www.annualreviews.org/content/journals/10.1146/annurev-biochem-052521-042909
#Biochemistry #Structure #cryoEM #Chemistry #ChemBio
CC: @gdch, @GDCh_BioChem
How are the receptors in the synapse organized?
Diego Ortiz-LĂłpez from the Hermann Schindelin group discussed his research at #Biochemistry2026. He talked about the organization of receptors in the inhibitory postsynapse by organization of gephyrin oligomers.
https://www.biorxiv.org/content/10.1101/2025.09.01.673457v1
#Biochemistry #cryoEM #Structure #Synapse #Chemistry #ChemBio
CC: @gdch, @GDCh_BioChem
