CANYA AI Decodes the Language of Sticky Proteins | Geekoo

A groundbreaking AI model trained on 100,000 synthetic protein sequences reveals new insights into what makes proteins clump, opening the door to better drugs and deeper understanding of diseases like Alzheimer’s.

A new way to measure ageing and disease risk with the protein aggregation clock

A new way to measure ageing and disease risk with the protein aggregation clock

Neues Verständnis von Altern und Krankheitsrisiko mithilfe der Proteinaggregationsuhr

A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans

This study shows that during failure of core protein quality control in C. elegans, a specialized anti-aggregation mechanism relying on intracellular pathogen response factors and lysosomal mediated degradation is triggered, promoting tissue-specific resilience to age-dependent protein aggregation and its proteotoxicity.

Dementia risk linked to blood-protein imbalance in middle age

Abnormal levels of certain proteins — many of which have roles outside the brain — could be an early hallmark of Alzheimer’s disease or similar conditions.