🧬 What new insights can AI reveal about genetic risk factors for Alzheimer’s disease?

🔗 DuAL-Net: A Dual-Network Approach for Alzheimer’s Disease Risk Prediction Using APOE-Centered Regional Whole-Genome Sequencing Data. Computational and Structural Biotechnology Journal (CSBJ). https://spj.science.org/doi/epdf/10.34133/csbj.0010

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AlzheimersResearch #Genomics #AIinHealthcare #PrecisionMedicine #Neuroscience

This brief highlights a novel cellular mechanism implicated in neurodegenerative risk, offering insight into how brain clearance processes may influence dementia trajectories. For mental health professionals, the finding illuminates potential links between neurobiology and cognitive-emotional functioning, underscoring the relevance of cellular-level factors in brain resilience and vulnerability.

Article Title: Scientists discover hidden brain cells that may stop Alzheimer’s tau buildup

Link to Science Daily Mind-Brain News: https://www dot sciencedaily dot com/releases/2026/03/260307155945 dot htm

#neurodegeneration #tauopathy #tanycytes #brainhealth #alzheimersresearch

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Monster In The Mind (Alzheimer's Documentary) | Real Stories

https://peertube.gravitywell.xyz/w/xbHKu4GA9q1C7McdZBW8h4

New research highlights a hidden, early-warning sign for Alzheimer's that has nothing to do with memory. It happens at night, and detecting it could be crucial for future interventions.

#dementia #alzheimers #alzheimersResearch #Neuroscience #Health

https://www.futura-sciences.com/en/alzheimers-this-hidden-nighttime-disruption-begins-long-before-memory-loss_23040/

🚀 What if we could precisely target the CAPON–nNOS axis — a pathway long considered undruggable?

🔗 Targeting CAPON to modulate the CAPON–NOS Axis: a computational approach. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.001

📚 CSBJ: https://www.csbj.org/

#DrugDiscovery #ComputationalBiology #AlzheimersResearch #Neuroscience #ProteinProteinInteractions #VirtualScreening #MolecularDynamics #AIinDrugDiscovery

🧬 Could a new form of amyloid aggregation change how we understand Alzheimer’s disease?

🔗 Aggregation dynamics of a 150 kDa Aβ42 oligomer: Insights from cryo electron microscopy and multimodal analysis. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.11.024

📚 CSBJ: https://www.csbj.org/

#CryoEM #ProteinAggregation #Biophysics #StructuralBiology #AlzheimersResearch #Neuroscience #DrugDiscovery #AmyloidBeta