Immunity-linked genes expressed differently in brains of autistic people | Spectrum | Autism Research News
Postmortem brain samples from people with one of six conditions, including autism, show distinct signatures of over- and underexpression of immune genes.
Highly expressed genes may buffer against autism-linked mutations in girls | Spectrum | Autism Research News
Such high expression levels may account for the condition’s sex bias, a new preprint suggests — but not everyone agrees with that logic.
Autism’s sex bias tied to glial, immune cell gene expression | Spectrum | Autism Research News
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.
Consistent, convergent pathways link two forms of autism | Spectrum | Autism Research News
People with dup15q syndrome and those with idiopathic autism have similar patterns of altered gene expression in early brain development and later in life.
Autism researcher Daniel Geschwind nets top National Academies prize | Spectrum | Autism Research News
The prize recognizes Geschwind’s contributions to our understanding of autism genetics.
Portrait of a research field: astrocytes in autism | Spectrum | Autism Research News
Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Inflammation may reshape brain regions tied to autism | Spectrum | Autism Research News
Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.
Histone-modifying drug improves autism-like behaviors in mice | Spectrum | Autism Research News
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
Searching for the biology behind autism’s sex bias | Spectrum | Autism Research News
The fact that autism seems to affect more boys than girls is often attributed to diagnostic gaps, but the skew remains largely unexplained. Some scientists are turning to basic biology for answers.
Alternate RNA versions of genes may shape autism | Spectrum | Autism Research News
Autism may involve different levels of RNA isoforms encoded by genes in the brain, which express many more proteins than previously thought.
Autism News International