Mastodawn

Researchers engineered a virus-mimicking dual-layer nanoparticle to condense and protect #nucleic acids, then subjected the formulation to #lyophilization (freeze-drying) and storage at -20°C to validate its stability and rehydration properties.
#Oncology #Chemistry #Pharmaceutical #Nanotechnology #sflorg
https://www.sflorg.com/2026/01/ongy01162601.html

Purdue mRNA therapy delivery system proves to be shelf-stable, storable

These results could address challenges faced by lipid nanoparticle delivery systems

Technische Universität München Sep 26

In the second episode of our new EXplained series, we highlight the #ClusterofExcellence NUCLEATE. At our #university, it is represented by Stefan Engelhardt, who shares insights into #nucleic-acid based #medicine: http://go.tum.de/139582

#nucleicacids

📷 ProLehre

Nucleic acids as key to a new class of drugs

In our "EXplained" video series, we present the seven Clusters of Excellence with which our university is entering the next funding phase of the Excellence Strategy. In the second episode, we get to know the new cluster NUCLEATE, which is represented at TUM by Prof. Stefan Engelhardt.

Bose-Einstein-Kondensat Jun 29, 2025

Bio-On-Magnetic-Beads (BOMB): #OpenSource platform for high-throughput #nucleic acid #extraction & manipulation:

-synthesis of functionalised #MagneticBeads
-HT #purification of #RNA & #DNA from a range of #bacterial, #animal, #plant, #environmental & #synthetic sources
-bead-based protocol for #bisulfite conversion & size selection of DNA & RNA fragments

Article: https://doi.org/10.1371/journal.pbio.3000107
Web: https://bomb.bio/
#DIYbio #DIYchem #chemistry #magnetic #lab #instruments

Scientific Frontline Mar 6, 2023

#Cell membranes are barriers that maintain #cellular #homeostasis, and the intracellular delivery of biologically functional #molecules, including #peptides, #proteins, and #nucleic acids to manipulate cellular functions.
#Medical #Nanotechnology #Cancer #sflorg
https://www.sflorg.com/2023/03/med03062302.html

Light-Induced Acceleration of Intracellular Delivery

Cell membranes are barriers that maintain cellular homeostasis

Scientific Frontline Feb 6, 2023

#Nucleic acid-targeting #photodynamic therapy (#PDT) is a promising type of targeted therapy that is being actively researched. This treatment relies on special #photosensitizers, a type of drug that binds at specific locations in a #cell's #DNA.
#Cancer #Medical #sflorg
https://www.sflorg.com/2023/02/med02062302.html

Mapping How Singlet Oxygen Molecules Travel Along DNA Strands

Nucleic acid-targeting photodynamic therapy (PDT)

Prof Antony Feb 3, 2023

Right on the heels of the @Fusion_Conf on Homologous Recombination in Portugal!!
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RT @mages05
Reg now open! Talk #Cancer #Aging #DNAReplication #Translation #GeneExpression at The Helicases and #Nucleic Acid-based Machines Conf. 7/16-20 #HNASRC

Abstracts Due: 5/14
Info: http://bit.ly/3JJ5hK1
Organizers: @bethtran76 @Trakselis @PaeschkeLab
Keynote: @PatrickSungLab https://twitter.com/taekjip/status/1575285593998622721
https://twitter.com/mages05/status/1621525464400420864