Mastodawn

What is the evolutionary significance of alternative #transcription initiation, #splicing & #polyadenylation? This study of 75 metazoan species suggests that most transcript diversity reflects deleterious RNA processing errors rather than adaptive function @PLOSBiology plos.io/3Pcs2e6

GDCh Division of Biochemistry 5d ago

Xinlai Cheng gave an interesting talk at #Biochemistry2026. He talked about his group's research into "Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation".

https://onlinelibrary.wiley.com/doi/10.1002/anie.202516809
#Splicing #Biochemistry #Chemistry #ChemBio
CC: @gdch

Paul SomeoneElse Feb 19

I like this definitions of quasiquote and unquote and unquote-splicing:

https://www.scheme.com/tspl4/objects.html#./objects:h0

I referenced that, but I am looking at it in my paper book, and
the web page looks better because the backtick is more obvious in
my browser. The backtick in my paper book looks the same as
a normal single quote.

But that's not really a problem if anything maybe it makes
me dwell on it longer.

#scheme #quasiquote #unquote #splicing

Operations on Objects

News Beep Dec 18

Gestational diabetes alters the placenta at the molecular level, study reveals

Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely…
#NewsBeep #News #Headlines #diabetes #genes #Genetic #gestationaldiabetes #IL #Israel #Medicine #placenta #pregnancy #Protein #RNA #Splicing
https://www.newsbeep.com/318672/

Hambone Fakenamington Oct 27

#Splicing #Altnet #Altnets #RuralBroadband

Hambone Fakenamington Oct 19

144 fibres spliced so there are usable connectors on the end :)

That was my Sunday (with generous help from my friend too, pretty much halves the time needed if you have help!).

#Altnet #Altnets #RuralBroadband #Fibre #Splicing #Fiber

T_X Oct 4

All parts for the first self-made #fiber line for our "housing" project have been ordered, we can hopefully start with the installation on Tuesday.
If those cold "splicing" quickconnect/fastconnect connectors don't work, does anyone know someone in #Lübeck or #Hamburg who could lend a fiber #splicing device?

Planetární ekolog Sep 12, 2025

Alternativní splicing (Genetika 🧬)

Alternativní splicing je jev, při němž při transkripci vzniká z jednoho genu více variant mRNA potenciálně kódujících rozdílné bílkovinné produkty. Po přepisu DNA v jádře prochází tzv. primární transkript RNA úpravami, v jejichž rámci se dlouhé nekódující úseky vystřihují a ostatní sekvence je možné spojit různými způsoby. Z výsledných několika RNA vytvořených od...

https://cs.wikipedia.org/wiki/Alternativní_splicing

#AlternativniSplicing #Genetika #Splicing

Alternativní splicing – Wikipedie

Sustainable Sailing Aug 27, 2025

New #Video
Can we safely stretch our 12mm #Dyneema #DIY Main Mast #shrouds & stays?
After Jane did all the #splicing for the main mast #rigging, we had to stretch everything
https://www.sustainablesailing.net/new-video-4/

New Video: Can we safely stretch our 12mm Dyneema DIY Main Mast shrouds & stays?

After Jane did all the splicing for the main mast rigging we had to stretch everything

Sustainable Sailing

TechPotli Jul 10, 2025

Maxxtek N300 Single Band Router | GPON ONT with FXS Port | 300Mbps 2.4GHz
👉𝐒𝐡𝐨𝐩 https://techpotli.com/.../maxxtek-n300-single-band.../
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