James Watson died a few days ago.
In 1953, together with Francis Crick, he had published a short text in โNatureโ. It is written in a subdued style. One of the first sentences says โThis structure has novel features which are of considerable biological interestโ; another sentence is โSo far as we can tell, it is roughly compatible with the experimental data, but it must be regarded as unproved until it has been checked against more exact results".
This was the first published description of the structure of DNA as a double helix. In 1962, Watson, Crick and Maurice Wilkins were awarded the Nobel Prize (unfortunately, the key role of Rosalind Franklin was not appreciated at the time). A few decades later, when the enormous importance of their discoveries is already known, it feels strange to read such cautious phrases: โnovel featuresโ, โconsiderable biological interestโ, โit must be regarded as unprovedโ.
But this is the language of basic research that changes the world. And that is why this research needs to be financed, even though it does not immediately bring spectacular results.
Watson and Crickโs article (extremely brief): https://www.nature.com/articles/171737a0.epdf
On the role of Rosalind Franklin: https://www.nature.com/articles/d41586-023-01313-5?
On racism and sexism in Watson's later life: https://www.statnews.com/2025/11/07/james-watson-remembrance-from-dna-pioneer-to-pariah/
#biology
#science
#DNA
#basicresearch