Sicilianews24.it: Mastectomia radicale vs. mastectomia radicale modificata: le principali differenze

La mastectomia è un intervento chirurgico che prevede la rimozione di uno o entrambi i seni. Questa procedura può essere necessaria per vari motivi, che analizzeremo di seguito, tenendo conto delle diverse esigenze che possono portare a questa decisione.
Motivi per cui è necessaria la mastectomia
Uno dei principali motivi per cui si ricorre alla mastectomia è la presenza di un tumore al seno. Infatti, questa operazione rappresenta una delle terapie più comuni per il carcinoma mammario. La diagnosi precoce e l’intervento tempestivo possono fare la differenza nella prognosi e nel recupero della paziente.
Un secondo motivo è rappresentato dalla prevenzione. Le donne che presentano un elevato rischio di sviluppare tumore al seno, per esempio a causa di fattori genetici come la mutazione dei geni BRCA1 o BRCA2, potrebbero optare per una mastectomia preventiva. Questa scelta è spesso discutibile e richiede un colloquio approfondito con specialisti del settore.
Interventi di riassegnazione di genere e altre condizioni

L'articolo Mastectomia radicale vs. mastectomia radicale modificata: le principali differenze sembra essere il primo su Sicilianews24.it.

Radical mastectomy vs. modified radical mastectomy: the main differences

Mastectomy is a surgical procedure that involves the removal of one or both breasts. This procedure may be necessary for various reasons, which we will analyze below, taking into account the different needs that may lead to this decision.

Reasons for Mastectomy

One of the main reasons for resorting to mastectomy is the presence of a breast tumor. Indeed, this operation represents one of the most common therapies for breast cancer. Early diagnosis and timely intervention can make a difference in the patient’s prognosis and recovery.

A second reason is represented by prevention. Women who are at high risk of developing breast cancer, for example due to genetic factors such as the mutation of genes BRCA1 or BRCA2, may opt for a preventative mastectomy. This choice is often debated and requires a thorough consultation with specialists in the field.

Gender reassignment procedures and other conditions

The article “Radical Mastectomy vs. Modified Radical Mastectomy: the main differences” appears to be the first on Sicilianews24.it.

#second #BRCA1 #BRCA2 #first

https://www.sicilianews24.it/mastectomia-radicale-vs-mastectomia-radicale-modificata-le-principali-differenze-828122.html

Mastectomia radicale vs. mastectomia radicale modificata: le principali differenze

La mastectomia è un intervento chirurgico che prevede la rimozione di uno o entrambi i seni. Questa procedura può essere necessaria per vari motivi, che

Sicilianews24.it
Genetically Significant Hereditary Mutations Associated with Breast and Ovarian Cancer among Ukrainian Women - #breastcancer #ovariancancer #hereditarymutation #BRCA1 #BRCA2 #CHEK2 #Ukraine #cancer #genetics #mutations - https://link.springer.com/article/10.3103/S009545272601007X
Genetically Significant Hereditary Mutations Associated with Breast and Ovarian Cancer among Ukrainian Women - Cytology and Genetics

Abstract The study of mutations associated with the syndrome of hereditary breast cancer (BC) and ovarian cancer (OC) is extremely important for understanding the genetic risks among Ukrainian women. In this work, we conducted NGS study of mutations in the genes associated with the syndrome of hereditary BC and OC in 1090 women who had indications for testing and 407 women from the control group. As a result of the study, 233 patients with mutations were identified, including 84 unique variants. The largest number of mutations was registered in the BRCA1 (102), BRCA2 (42), and CHEK2 (67) genes. In the BRCA1 gene, the following mutations were the most frequent: c.5266dup (p.Gln1756fs), 45 cases; c.181T>G (p.Cys61Gly), 13; c.1510del (p.Arg504fs), 6; c.4035del (p.Glu1346fs), 5. The BRCA1 gene is a key risk factor for the development of cancer at a young age, while the CHEK2 is more frequently associated with cancer at an older age. The Population Attributable Risk (PAR) for the BRCA1 is 7.49%, which makes this gene a major risk factor. The odds ratio for mutations in the CHEK2 is 1.84 (95% CI: 1.01–3.34), while the PAR is 2.2%. The highest frequency of mutations (BRCA1 and BRCA2) was registered in the Central region of Ukraine. We for the first time performed a large-scale genetic study of the prevalence of hereditary mutations associated with the syndrome of hereditary BC and OC in Ukraine, the frequency of the most common mutations in the studied and control cohorts were determined.

SpringerLink
Alberta twins share 10-year breast cancer battle: ‘She gets it’
Born just five minutes apart, identical twins Connie Claeys and Cortney Drover have done everything together -- including a decade-long battle with breast cancer.
#cancer #family #health #Alberta #Features #brca2
https://globalnews.ca/news/11405740/alberta-twins-share-breast-cancer-battle/
#13Junio ☕ con buenas noticias vía @elpais.com "Premio Princesa de Asturias de Ciencia a #Mary_ClaireKing y su genética del #cáncer" "El #ADN mitocondrial era un rastro invisible que desbarató el plan de los represores" #AbuelasdelaPlazadeMayo #cáncerdemama #BRCA1 #BRCA2
SciTech Chronicles. . . . . . . . .Mar 8th, 2025

  From the lab to the street,trust in science not deceit.. Vol II No 61 299 links Curated Scientists upends understanding of how anticancer ...

BRCA Testing Cost | BRCA Gene Testing Cost

Explore the BRCA Testing Cost, BRCA Gene Testing Cost, BRCA 1 and 2 Testing Cost, and BRCA Testing Cost in India.

Proud to be part of #270Reasons & join writers supporting #KamalaHarris. Health care must be more than a "concept." New technology means we not only learn about current health issues but also about future challenges. My kids have a #BRCA2 mutation, meaning a sharply increased cancer risk. #HarrisWalz2024 get it 270reasons.com
[ODYSSEA] Une matinée de sport et de pensées positives !
Je suis contente,fière de moi et ca m'a fait du bien 👍💖😀
J'ai bien marché et j'ai pensé à tous ceux/celles qui se sont battus, se battent encore ou qui ont gagné contre ces putains de cancers ...
J'ai pensé aussi à toutes et tous qui sont comme moi atteinte du gène BRCA2.
Papa, Christian, Gigi, Lucille, Murielle, Jean, Estelle, Séverine et tous les autres
#odyssea #cancer #octobrerose #ratp #bougetesfessespoulette #ensembleonestplusfort #brca2 #brca2positive
#Scientists Find a 'Missing Link' Between Poor #Diet and Higher #Cancer Risk
Science Alert reports that a team of researchers found "that changes in #glucose #metabolism could help cancer grow by temporarily disabling a gene that protects us from #tumors called #BRCA2
https://www.sciencealert.com/scientists-discover-a-missing-link-between-diet-and-cancer-risk
Scientists Discover a Missing Link Between Diet And Cancer Risk

A previously unknown mechanism for inactivating genes that suppress tumor formation helps explain why cancer risk is associated with an unhealthy diet or unmanaged metabolic conditions like diabetes.

ScienceAlert

“Researchers from Singapore and the UK used mouse models, human tissue, and human breast organoids grown in the lab to find that changes in glucose metabolism could help cancer grow by temporarily disabling a gene that protects us from tumors called BRCA2.” #BRCA2 #dna #isogg #genetics #geneadons #cancer #tumors #glucose

https://www.sciencealert.com/scientists-discover-a-missing-link-between-diet-and-cancer-risk

Scientists Discover a Missing Link Between Diet And Cancer Risk

A previously unknown mechanism for inactivating genes that suppress tumor formation helps explain why cancer risk is associated with an unhealthy diet or unmanaged metabolic conditions like diabetes.

ScienceAlert