#GumDisease bacteria can promote #cancer growth in mice
Human #breastcancer cells with a #BRCA1 mutation could be more susceptible to damage, lab experiments suggest
The work suggests that harmful bacteria in the mouth may enter the bloodstream, make a beeline for breast tissue and then whomp healthy cells like a wrecking ball. Previous studies have turned up correlations between oral disease and breast cancer, but “now we have a direct connection”
https://www.sciencenews.org/article/gum-disease-bacteria-breast-cancer
https://archive.ph/XZLwp
Gum disease bacteria can promote cancer growth in mice

In mice, the oral bacteria F. nucleatum can travel to mammary tissue via the bloodstream, where it can damage healthy cells.

Science News
#13Junio ☕ con buenas noticias vía @elpais.com "Premio Princesa de Asturias de Ciencia a #Mary_ClaireKing y su genética del #cáncer" "El #ADN mitocondrial era un rastro invisible que desbarató el plan de los represores" #AbuelasdelaPlazadeMayo #cáncerdemama #BRCA1 #BRCA2
SciTech Chronicles. . . . . . . . .Mar 8th, 2025

  From the lab to the street,trust in science not deceit.. Vol II No 61 299 links Curated Scientists upends understanding of how anticancer ...

BRCA Testing Cost | BRCA Gene Testing Cost

Explore the BRCA Testing Cost, BRCA Gene Testing Cost, BRCA 1 and 2 Testing Cost, and BRCA Testing Cost in India.

Everyone has #BRCA1 and #BRCA2 genes, but mutations in these #genes - which can be inherited - increase the risk of #breast and #ovarian #cancer
#Genetics #Biology #Medical #sflorg
https://www.sflorg.com/2024/03/gen03292401.html
‘Exhausted’ immune cells in healthy women could be target for breast cancer prevention

We’re very excited about this discovery, because it opens up potential for a preventative treatment other than surgery for carriers of BRCA

MR Imaging Saves Breast Cancer Patients: Those with BRCA1 breast cancer enjoy a 3.5-fold lower risk of mortality compared with those not monitored with MR. #breast #cancer #BRCA1 #MR #magneticresonance #imaging #mortality
https://www.instagram.com/p/C4gQ6IVr85r/

I #learned from my own #diagnosis you can still get #BreastCancer with no #familyhistory.

The author thought no family history of breast cancer meant she wasn't at risk for the disease. But then she was diagnosed with stage-one #cancer.

#Women #Transgender #LGBTQ #LGBTQIA #Health #Healthcare #Cancer #BreastCancer #BRCA1 #BRCA2

https://www.insider.com/no-family-history-breast-cancer-diagnosis-2023-10

No family history of breast cancer doesn't mean you can't get disease

The author thought no family history of breast cancer meant she wasn't at risk for the disease. But then she was diagnosed with stage-one cancer.

Insider

A #transcription-independent mechanism -#RBM10-mediated RNA alternative #splicing coupled to nonsense-mediated #mRNA decay- determines rapid periodic fluctuations of #BRCA1 expression throughout the #cellcycle

https://www.embopress.org/doi/full/10.15252/embj.2022111951

Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
Sam Witus, Rachel Klevit, Weixing Zhao et al
https://www.embopress.org/doi/10.15252/embj.2023113565

EXO1 to the rescue: How does #EXO1 save #BRCA1-deficient cells?

The team of Profs. H. van Attikum & S.M. Noordermeer shows that BRCA1-deficient cells are unable to overcome damage if EXO1 is deleted. #preprint

#preLight by Jennifer Ann Black: https://prelights.biologists.com/highlights/exo1-mediated-dna-repair-by-single-strand-annealing-is-essential-for-brca1-deficient-cells/

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells - preLights

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

preLights