“The pharmacological approach in this study, however, uses a pharmacologic agent (P7C3-A20) that enables cells to maintain their proper balance of #NAD+ under conditions of otherwise overwhelming stress, without elevating NAD+ to supraphysiologic levels.” #ISOGG #DNA #geneadons https://case.edu/news/new-study-shows-alzheimers-disease-can-be-reversed-achieve-full-neurological-recovery-not-just-prevented-or-slowed-animal-models

“By using state-of-the-art DNA techniques and newly published genomes, we were able to determine the ancestry of the Beachy Head Woman with much greater precision than before,” William reveals.” #ISOGG #DNA #AncientDNA #BeachyHeadWoman #UK #geneadons https://www.nhm.ac.uk/discover/news/2025/december/the-changing-story-beachy-head-woman.html

My favourite #genealogy find this year was tracing the Fairbanks family line. It is a famous family but my line was missing a connection in the published book. Turns out that one Samuel Fairbanks was born out of wedlock. Confirmed with birth record and the probate records who was listed as mother, wife and children. All matched the rest of the details in the book. Same with Hannah Breck who also had a published genealogy. Now I can confidently fill in some details and move past that wall. What is your best research find? Best wishes for the New Year! #genealogy #Geneadons #FamilyHistory

Got a lovely note today from a client whose final report I sent out a couple of days ago, thanking me for my work and happy that I answered a longstanding question. I don't get many complaints, so I can only guess that most of my clients are satisfied. But it's really nice to hear it now and then. #Genealogy #Geneadons

Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia, whereas low-fat cheese. APOE ε4 status modified the association between high-fat cheese and AD. Our study's observational design limits causal inference” #ISOGG #DNA #epigenetics #dementia #geneadons #alzheimers #cheese #brie #cheddar #cognitivedecline https://www.neurology.org/doi/10.1212/WNL.0000000000214343

Just finished watching the fascinating documentary “Secrets of the Neanderthals” on Netflix. Not a lot of DNA discussion but there is one part where they can identify whether the remains are male or female based on a dental protein. #DNA #ISOGG #neanderthals #Netflix #ShanidarZ #geneadons Here’s a link to the trailer: https://youtu.be/b5YtgLSU_sE?si=Ua4xg54r3hnrEdgQ

“In individuals with adequate TRPM7 function, Mg supplementation increases the abundance of C. maltaromaticum and F. prausnitzii.” #DNA #ISOGG #epigenetics #coloncancer #colorectalcancer #magnesium #TRPM7 #geneadons
https://www.sciencedirect.com/science/article/pii/S0002916525005271?via%3Dihub

#GenChat @genchat Sorry to slip out early but will check back later for last of the Q&As and comments! Have a good weekend, #Geneadons & ty to Christine for hosting 😀