@DenisCOVIDinfoguy

Hello! Thanks again for all of your incredible work.

I've just completed a week of nicotine patches (very low dose) for what the GP thinks is #LongCOVID however, I really don't think it is (symptoms started 2 days after Shingrix vaccine, so....). Anyway, the patches didn't do anything for me (maybe b/c I don't have LC?) but I've read they do work for others for #dysautomnia #autonomic issues.

So, I've finally (finally!) found a doctor who has listened and appears to be on the right track.

After 12months of symptoms that are, at times, very difficult to live with, I appear to have a diagnosis, of sorts.

I have the #autonomic (#dysautomnia really) symptoms of #LongCOVID despite NOT having had #COVID19 (to my knowledge). Having a COVID vaccine followed by a shingles vaccine one week later was the trigger.

The treatment?

Nicotine patches! Worth a try!

https://pubmed.ncbi.nlm.nih.gov/36650574

Is the post-COVID-19 syndrome a severe impairment of acetylcholine-orchestrated neuromodulation that responds to nicotine administration? - PubMed

Following a SARS-CoV-2 infection, many individuals suffer from post-COVID-19 syndrome. It makes them unable to proceed with common everyday activities due to weakness, memory lapses, pain, dyspnea and other unspecific physical complaints. Several investigators could demonstrate that the SARS-CoV-2 r …

PubMed
NKVSSP SUNDAY

Fight, Flight, Freeze (and sometimes Fawn)

It's #tunetuesday so I thought I would share an old tracks of mine - big on the fediverse for some reason (thanks @radiofreefedi!)

Get the rest of the tracks from this collab album with Shin Bone here: https://audio.enoent.one/tenonev1-5/

All tunes free forever here:
https://audio.enoent.one/

#dnb #autonomic #bass

Among 491 individuals with no prior history of #autonomic disorders:
🔹 44% developed an autonomic disorder after COVID-19
🔹 75% of these had new onset POTS
https://link.springer.com/article/10.1007/s10286-025-01111-1
Chronic autonomic symptom burden in long-COVID: a follow-up cohort study - Clinical Autonomic Research

Purpose Autonomic dysfunction is a common and often debilitating feature of long-COVID (LC), however, studies evaluating frequency and severity of chronic autonomic dysfunction in LC are limited. We utilized an established online cohort of participants with LC to assess duration and severity of autonomic dysfunction, impact on quality of life, risk factors of autonomic diagnoses including postural tachycardia syndrome (POTS), and efficacy of common treatments. Methods Our international cohort included 526 adults with LC aged 20–65 years who previously completed baseline evaluations of LC symptoms, autonomic symptom burden, and quality of life. Participants repeated survey instruments and completed new instruments assessing risk factors and symptom mitigation strategies. A subset of individuals completed a 10-min active stand test. Multivariable logistic regression identified predictors of autonomic symptom burden and incident autonomic diagnoses including POTS. Results A total of 71.9% of participants with LC had a Composite Autonomic Symptom Score-31 (COMPASS-31) score ≥ 20, suggestive of moderate-to-severe autonomic dysfunction. The median symptom duration was 36 [30–40] months, and 37.5% of participants could no longer work or had to drop out of school due to their illness. In addition, 40.5% of individuals with autonomic dysfunction were newly diagnosed with POTS, representing 33% of the total LC cohort. Female sex and joint hypermobility were associated with an increased risk of autonomic dysfunction. Conclusions Evidence of chronic moderate-to-severe autonomic dysfunction was seen in most participants with LC in our cohort and was significantly associated with reduced quality of life and functional disability. POTS was the most common post-COVID autonomic diagnosis.

SpringerLink

💓 60-second heartbeat recordings offer window into autonomic health after severe brain trauma

https://medicalxpress.com/news/2024-09-heartbeat-window-autonomic-health-severe.html

#tbi #autonomic #stress #heatbeart #medicine #research

60-second heartbeat recordings offer window into autonomic health after severe brain trauma

For the over 1 million Americans who survive severe traumatic brain injuries each year, the road to recovery is often long and challenging. Disruption of the autonomic nervous system, which controls involuntary functions like heart rate, is a common yet poorly understood consequence of TBI.

Medical Xpress
I'm loving my new professional music making toy. Roland SP 404 MKII. #SP404MK2 #sampler #sampling #drumnbass #autonomic #jam #electronicmusic

wanna know why western democracies consider sleep deprivation to be a form of physical and psychological torture?

after a certain point even the strongest of minds will capitulate, they will fold, and they will admit to whatever is demanded just to be able to rest. they may have no recollection, no memory, nor cognitive capacity to comprehend the passage of time... the brain eventually shuts down non-critical functions, leaving only the autonomic nervous system to maintain its most basic functions.

they'll give you five minutes that feels like an hour, six that feels like a month, but never truly rest, prodded back to the conscious realm to simply say, "yes... yes, yes... just leave me be..."

what may remain of those scattered memories? just rest your head little one, and you may see, in the mind's eyes, that nothing ever changed... "WAKE UP! five minutes!"

#ptsd #trauma #insomnia #sleep #dreaming #terror #neurology #catecholamines #neurotransmitter #adrenergic #autonomic

"NIH opens long COVID trials to evaluate treatments for autonomic nervous system dysfunction"

https://www.nih.gov/news-events/news-releases/nih-opens-long-covid-trials-evaluate-treatments-autonomic-nervous-system-dysfunction

"Part of NIH’s RECOVER Initiative, trials will test at least three treatments for symptoms such as fast heart rate, dizziness and fatigue."

@longcovid

#COVID #LongCovid #POTS #Dysautonomia #Autonomic #Research #NIIH

NIH opens long COVID trials to evaluate treatments for autonomic nervous system dysfunction

Part of NIH’s RECOVER Initiative, trials will test at least three treatments for symptoms such as fast heart rate, dizziness and fatigue.

National Institutes of Health (NIH)

*Virtual Option* Conference, this weekend, register ASAP.

#Dysautonomia #POTS & #autonomic disorders are very common in #LongCovid patients - everyone should be interested.

We invite you to join Dysautonomia International for the world's largest conference on autonomic nervous system disorders, July 14-17, 2023 in metropolitan Washington, DC! Guests will enjoy a fantastic weekend of educational seminars, engaging speakers, and social events July 14-16, followed by Dysautonomia Advocacy Day on Capitol Hill on July 17. This event brings together patients, caregivers, researchers, clinicians, industry representatives, and non-profit leaders and government policy makers. In-person and virtual registration options are available.

(Virtual registration includes access to recordings of sessions.)

https://www.dysconf.org/

2023 Dysautonomia International Conference: Advocacy in Action

We invite you to join Dysautonomia International for the world's largest conference on autonomic nervous system disorders, July 14-17, 2023 in metropolitan Washington, DC! This event brings together patients, caregivers, researchers, clinicians, industry representatives, and non-profit leaders and government policy makers.

DysConf2023