The prospect of a better treatment for Chagas disease and sleeping sickness https://blogs.biomedcentral.com/bugbitten/2023/07/21/the-prospect-of-a-better-treatment-for-chagas-disease-and-human-african-sleeping-sickness/
#Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections https://www.science.org/doi/10.1126/science.adh0614
"#NeglectedTropicalDiseases caused by #SingleCelled #parasites (#trypanosomatids) include #ChagasDisease, #SleepingSickness & #leishmaniasis. Progress in treatment of these #diseases had been slow, though large chemical library screens are now showing promising results."
#ClimateCrisis: Acidifying oceans will cause a diversity and survival crisis for microscopic marine organisms https://phys.org/news/2023-07-acidifying-oceans-diversity-survival-crisis.html #protists #microbes #ClimateChange
Biocalcification crisis in the continental shelf under #OceanAcidification https://www.sciencedirect.com/science/article/pii/S1674987123000890
"#SingleCelled organisms known as #foraminifera produce chambered #shells of calcium carbonate, and they are an important part of marine food chains... New research has focused on the impact of #acidification on benthic #forams"
Oceanic responses to climate and human interactions have been studied for decades. In recent years the effects of increasing ocean acidity have been featured, with stark images of coral reefs being decimated by bleaching.
Giant proteins in a giant cell: Molecular basis behind fastest biological movement in single-celled #eukaryotes https://phys.org/news/2023-02-giant-proteins-cell-molecular-basis.html
Giant #proteins in a giant cell: Molecular basis of ultrafast Ca2+-dependent cell contraction https://www.science.org/doi/10.1126/sciadv.add6550
"#Spirostomum, is a genus of millimeter-scale #SingleCelled #protists that are known for their incredibly rapid movement. They are capable of some of the fastest movement in the biological world due to their ultrafast contraction."
In his famous letter to the Royal Society dated Oct. 9, 1676, Antonie van Leeuwenhoek described a single-celled eukaryote (Vorticella) and its fascinating ultrafast cell contraction. This kind of ultrafast cell contraction triggered by a Ca2+-dependent mechanism is distinct from the adenosine triphosphate (ATP)-dependent mechanisms found in actin-myosin and dynein/kinesin-tubulin systems.
Hello! I'm a #PostDoc in evolutionary #protistology. I study #evolution, #biodiversity, and #symbiosis in #protists ( = eukaryotic #microbes = #SingleCelled critters more complex than bacteria - eg. #amoebae, #ciliates, #flagellates, #microalgae, etc.) mostly using #genomics and #bioinformatics.
I come from #Prague, CZ & currently live in #Orsay, FR.
I'm interseted in #diversity & #evolution of all life, #earth & #space #science, #languages, #religion, #progressive politics.