Mastodawn

#biology #medicine #phages #EscherichiaColi

An article published in the journal "Microbiology Spectrum" reports the results of experiments based on the use of genetically modified #bacteriophage #viruses to combat strains of Escherichia coli #bacteria that developed resistance to various antibiotics. These findings offer a way to neutralize these bacteria and new insights into the interactions between bacteriophages and bacteria.

https://english.netmassimo.com/2025/11/12/a-technique-based-on-the-use-of-genetically-modified-bacteriophage-viruses-to-fight-strains-of-bacteria-that-developed-resistance-to-antibiotics/

A technique based on the use of genetically modified bacteriophage viruses to fight strains of bacteria that developed resistance to antibiotics

An article published in the journal 'Microbiology Spectrum' reports the results of experiments based on the use of genetically modified bacteriophage viruses...

Daniel Hoffmann🌻Sep 20

One step closer to manufacturing #pandemics. The first successful AI-design of E. coli #phages with new properties. Applied by zealots to human pathogenic viruses ... and we have a solution to Fermi's paradox. https://www.nature.com/articles/d41586-025-03055-y

World’s first AI-designed viruses a step towards AI-generated life

Scientists used artificial intelligence to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.

Prof Paula Salgado Sep 3

Yesterday session on #Clostridia #phages and surfaces was brilliant, with personal highlights being Dr Anna Barwinska-Sendra's work on diversification of #Cdiff #S-layers, Louis-Charles Fortier's talk on how phage/S-layer specificity and Lea Huet's work in PSII S-layer anchoring. #clostpath14

The-14 Jul 29

How ancient viruses could help fight antibiotic resistance
#Health #Bacteria #Antibiotics #PhageTherapy #Phages #AntibioticResistance #AMR #Microbiology #Superbugs #InfectiousDiseases #BacteriaVsVirus #MedicalResearch #PublicHealth
https://the-14.com/how-ancient-viruses-could-help-fight-antibiotic-resistance/

Amelia Cervera 🧬Jul 23

Viromics approaches for the study of viral diversity and ecology in microbiomes.

#Virology #Viromics #Phages #GenomeResolvedMetagenomics

https://www.nature.com/articles/s41576-025-00871-w

Viromics approaches for the study of viral diversity and ecology in microbiomes - Nature Reviews Genetics

In this Review, Roux and Coclet outline current viromics approaches and discuss how they have contributed to our growing understanding of viral genomic diversity, focusing on uncultivated viruses of microorganisms.

Nature

Allen Tien, MD, MHS mdlogix.com 94,698 田一彦 Jul 1

#Phages www.linkedin.com/posts/michae...

It hunts without eyes. | Micha...

It hunts without eyes. | Michael Magri

It hunts without eyes. It walks without legs. But it’s one of the deadliest predators on Earth. Meet the bacteriophage — a virus that preys on bacteria. With a body that looks like a mechanical spider and a head shaped like a crystal, this microscopic assassin doesn’t infect humans… but it devastates bacteria. It lands on a bacterial cell, locks in like a lunar lander, then drills its tail through the cell wall and injects its genetic code like a virus syringe. Once inside, it hijacks the bacteria’s entire system — turning it into a factory for more phages. And when the host can’t handle it anymore? It bursts. Violently. This is biological warfare on a cellular level. And in an age of antibiotic resistance, bacteriophages might just become medicine’s most ancient — and most futuristic — ally.

preLights May 20

Defence mechanism inception!

Listeria prophages protect their host bacteria with anti-phage systems, leaving them susceptible to their own defence systems - read how this may actually be an evolutionary advantage!

#preLight from Briana Guzman, Noah Franz #ImmunobiologyUA ! ⬇️ 👀

👉 https://prelights.biologists.com/highlights/a-prophage-encoded-anti-phage-defense-system-that-prevents-phage-dna-packaging-by-targeting-the-terminase-complex/

#microbiology #immunobiology #bacteria #infection #phages #prophages

Charité Berlin May 16

#Phages (viruses that kill bacteria) are considered a potential approach to combat multidrug-resistant pathogens. However, they don't always deliver the desired results on their own. A research team at #CharitéBerlin has now demonstrated that combining phages with an antibiotic is much more effective, at least in the lab, against a form of #pneumonia caused by multidrug-resistant bacteria 💪👩‍🔬.

👉 https://www.charite.de/en/research/paper_spotlight/new_findings_on_phage_antibiotic_combination_therapy

#CharitéPaper #medicine #science #research #MedMastodon #AMR #antibiotics

New findings on phage-antibiotic combination therapy: Charité – Universitätsmedizin Berlin

Using lab experiments, researchers from Charité – Universitätsmedizin Berlin have gained new insights into the combination of phages and antibiotics to treat pneumonia. Here, Chantal Weissfuss, first author of the study, and study lead PD Dr. Geraldine No

Charité – Universitätsmedizin Berlin

Frank Aylward Apr 28

Exciting work from the Hsu lab at Virginia Tech! They developed a cool way too knock down phage abundances to examine their role in the gut.

"A bacteriophage-conditional mouse model reveals the impact of phages within a conventionally colonized gut microbiota"

https://www.sciencedirect.com/science/article/pii/S1931312825001350?dgcid=coauthor

#microbiome #microbiology #phages

PLOS Biology Apr 8

The BASEL collection of E. coli #phages is limited by its host strain. @aharms485 &co use a modified host to add 36 new phages, revealing roles of O-antigen in host recognition & R-M systems in immunity @PLOSBiology https://plos.io/4jirGvX

Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage–host interactions

The BASEL collection of phages that infect E. coli has been a valuable resource, but is limited by the peculiarities of the host strain used. This study uses a modified host to expand the collection with 36 new phages, revealing key roles of the O-antigen barrier in host recognition and restriction-modification systems in bacterial immunity.