Phage P100 resistance in clinical & foodborne Listeria monocytogenes isolates is associated with adsorption-inhibiting mutations & fitness trade-offs.

Study shows diverse P100 resistance mechanisms in #Listeria & significant serovar‑dependent fitness costs.

https://davidojcius.blogspot.com/2026/02/phage-p100-resistance-in-clinical-and.html #OpenAccess #bacteriophage #phage #food

Bacteriophage cocktail in drinking water suppresses systemic avian pathogenic Escherichia coli infection and pathology in laying hens.

High‑MOI phages cut APEC morbidity and mortality by 20–30%. Oral delivery worked best, removed lesions, lowered histology scores, and the cocktail stayed active without harming the cecal microbiota.

https://davidojcius.blogspot.com/2026/02/bacteriophage-cocktail-in-drinking.html #OpenAccess #microbiology #bacteriophage #phages #chickens

#Bacteriophage cocktail in drinking water suppresses systemic avian pathogenic Escherichia coli infection and pathology in laying hens

https://www.sciencedirect.com/science/article/pii/S2666517426000246 #OpenAccess #Ecoli #phages #microbiology

Molecular basis for anti-jumbo phage #immunity by AVAST type 5.

Avs5 detects an early jumbo‑phage activator and halts infection by rapidly hydrolyzing NAD+.

https://www.sciencedirect.com/science/article/pii/S1097276526000249 #phage #bacteriophage #microbiology

🧬 Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages

https://phys.org/news/2026-01-golden-gate-method-enables-fully.html

#molbio #virus #bacteriophage #bacteria #microbes #biotech #gmo

Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century. As antibiotic-resistant infections increasingly threaten public health, interest in bacteriophages as therapeutics has seen a resurgence. However, the field remains largely limited to naturally occurring strains, as laborious strain engineering techniques have limited the pace of discovery and the creation of tailored therapeutic strains.

Phys.org
Phage Explorer — Bacteriophage Genome Visualization

Visualize and analyze bacteriophage genomes with color-coded DNA/amino acid sequences, 3D structures, and 40+ analysis tools. Free, open-source, works offline.

Phage Explorer
Fighting Food Poisoning With A Patch

Food poisoning is never a fun experience. Sometimes, if you’re lucky, you’ll bite into something bad and realize soon enough to spit it out. Other times, you’ll only realize your …

Hackaday

#biology #medicine #phages #EscherichiaColi

An article published in the journal "Microbiology Spectrum" reports the results of experiments based on the use of genetically modified #bacteriophage #viruses to combat strains of Escherichia coli #bacteria that developed resistance to various antibiotics. These findings offer a way to neutralize these bacteria and new insights into the interactions between bacteriophages and bacteria.

https://english.netmassimo.com/2025/11/12/a-technique-based-on-the-use-of-genetically-modified-bacteriophage-viruses-to-fight-strains-of-bacteria-that-developed-resistance-to-antibiotics/

A technique based on the use of genetically modified bacteriophage viruses to fight strains of bacteria that developed resistance to antibiotics

An article published in the journal 'Microbiology Spectrum' reports the results of experiments based on the use of genetically modified bacteriophage viruses...