Mastodawn

How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @PLOSBiology https://plos.io/47Aripq

David Ojcius Feb 27

Phage P100 resistance in clinical & foodborne Listeria monocytogenes isolates is associated with adsorption-inhibiting mutations & fitness trade-offs.

Study shows diverse P100 resistance mechanisms in #Listeria & significant serovar‑dependent fitness costs.

https://davidojcius.blogspot.com/2026/02/phage-p100-resistance-in-clinical-and.html #OpenAccess #bacteriophage #phage #food

David Ojcius Feb 16

Bacteriophage cocktail in drinking water suppresses systemic avian pathogenic Escherichia coli infection and pathology in laying hens.

High‑MOI phages cut APEC morbidity and mortality by 20–30%. Oral delivery worked best, removed lesions, lowered histology scores, and the cocktail stayed active without harming the cecal microbiota.

https://davidojcius.blogspot.com/2026/02/bacteriophage-cocktail-in-drinking.html #OpenAccess #microbiology #bacteriophage #phages #chickens

David Ojcius Feb 16

#Bacteriophage cocktail in drinking water suppresses systemic avian pathogenic Escherichia coli infection and pathology in laying hens

https://www.sciencedirect.com/science/article/pii/S2666517426000246 #OpenAccess #Ecoli #phages #microbiology

David Ojcius Feb 7

Molecular basis for anti-jumbo phage #immunity by AVAST type 5.

Avs5 detects an early jumbo‑phage activator and halts infection by rapidly hydrolyzing NAD+.

https://www.sciencedirect.com/science/article/pii/S1097276526000249 #phage #bacteriophage #microbiology

Paul Houle Feb 1

🧬 Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages

https://phys.org/news/2026-01-golden-gate-method-enables-fully.html

#molbio #virus #bacteriophage #bacteria #microbes #biotech #gmo

Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century. As antibiotic-resistant infections increasingly threaten public health, interest in bacteriophages as therapeutics has seen a resurgence. However, the field remains largely limited to naturally occurring strains, as laborious strain engineering techniques have limited the pace of discovery and the creation of tailored therapeutic strains.

Phys.org

Hacker News Jan 31

Show HN: Phage Explorer
https://phage-explorer.org/
#ycombinator #phage #bacteriophage #bioinformatics #genome_visualization #DNA_sequence #amino_acid #lambda_phage #virology #microbiology

Phage Explorer — Bacteriophage Genome Visualization

Visualize and analyze bacteriophage genomes with color-coded DNA/amino acid sequences, 3D structures, and 40+ analysis tools. Free, open-source, works offline.

Phage Explorer

13 Jan 9

Fighting Food Poisoning With A Patch https://hackaday.com/2026/01/09/fighting-food-poisoning-with-a-patch/
#HackadayColumns #Science #Bacteria #Bacteriophage #Ecoli #Food #Foodpoisoning #Virus

Fighting Food Poisoning With A Patch

Food poisoning is never a fun experience. Sometimes, if you’re lucky, you’ll bite into something bad and realize soon enough to spit it out. Other times, you’ll only realize your …

Hackaday

Hackaday Jan 9

Fighting Food Poisoning With A Patch

https://web.brid.gy/r/https://hackaday.com/2026/01/09/fighting-food-poisoning-with-a-patch/