Gabriele Pollara5d ago
"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲 However... DOC.. more likely to be prescribed penicillin and less likely WHO β€œWatch” or β€œReserve” antibiotics #IDSky #ClinMicro #AMR

Direct Oral Challenge for Peni...
Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study

Abstract. In this international, multicenter prospective study, implementing penicillin direct oral challenge (DOC) using a digital toolkit was acceptable,

OUP Academic
Gabriele PollaraMar 28
Some real works of art here!!! #MicroSky #ClinMicro

RE: https://bsky.app/profile/did:plc:bzoexbcy5cvljh2npflko4ow/post/3mi3dbu3auc2z
Gabriele PollaraMar 23
We do quite a lot of antibiotic self administration in OPAT. Massive win if it can be achieved - lower requirements on hospital / community nurses & big autonomy win for the patients and their families. #OPAT #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:ihlofya6s7dijxbv242tjam6/post/3mhq73irnj22b
Gabriele PollaraMar 23
The Widal test drives typhoid over diagnosis and, by extension, unnecessary antibiotic prescriptions. Good piece in @[email protected] #IDSky #ClinMicro #AMR

The diagnostic void: how typho...
Gabriele PollaraMar 4
Well, that was effective use of social media time! Had totally forgotten about this webinar next Monday! Look forward to hearing from @[email protected] & @[email protected] #IDSky #ClinMicro #UTISky @[email protected]

RE: https://bsky.app/profile/did:plc:iuu7h4phnqvxwkiv36wbu4ll/post/3mgakcgctmc2w
Gabriele PollaraMar 2
Important letter in @[email protected] on use of cefalexin in treating pyelonephritis. Is it effective? What's the right dose? πŸ€·β€β™‚οΈ Key quote... πŸ‘‰ "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis." #IDSky #ClinMicro #AMR #UTISky

Cefalexin use in UK acute pyel...
Gabriele PollaraMar 2
Plasma cell free metagenomic sequencing to predict / diagnose blood stream infections. Neat & promising observational data. Even if unsurprising, remarkable to see increased detection of microbial genomic material as diagnosis nears. @[email protected] #IDSky #ClinMicro #UTISky #MedSky

Predicting bloodstream infecti...
Gabriele PollaraFeb 26
I was enjoying this bit of trivia about the origins of name sakazakii, but then the backstory on Cronos was .... 😲 #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:ao7ykaoap23gbmrggv4ytobn/post/3mfqscw2c7v2r
Gabriele PollaraFeb 20
Unexpected Friday bonus - new paper out (NOT peer reviewed)! Standardised antibiotic spectrum scores to: - quantify impact of antimicrobial stewardship rounds - prioritise patients for stewardship review Co-lead @[email protected] #IDSky #AMS #ClinMicro wellcomeopenresearch.org/articles/11-...
Gabriele PollaraJan 19
Cheery and scary title popped into my inbox. Not even disinfectants working?! 😨 "Molecular mechanisms of disinfectant resistance in Klebsiella pneumoniae" #ClinMicro #IDSky @[email protected] #MedSky #IPC academic.oup.com/jacamr/artic...

Molecular mechanisms of disinf...