Gene editing — Dec 2025 🧬
Big moves beyond classic CRISPR:
• In vivo editing of human stem cells
• New Cas systems expand the toolbox
• RNA editing without guide RNAs
• Screens uncover drug-resistance pathways
Full summary: https://pir.sh/pzy1bRB1lv
Gene editing — Dec 2025 🧬
Big moves beyond classic CRISPR:
• In vivo editing of human stem cells
• New Cas systems expand the toolbox
• RNA editing without guide RNAs
• Screens uncover drug-resistance pathways
Full summary: https://pir.sh/pzy1bRB1lv
🧬 Is the next revolution in precision medicine hidden in CRISPR’s conversation with the epigenome?
🔗 CRISPR-epigenetic crosstalk: From bidirectional regulation to therapeutic potential. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.031
📚 CSBJ: https://www.csbj.org/
#CRISPR #Epigenetics #GeneEditing #GenomeEngineering #MolecularBiology #EpigenomeEditing #PrecisionMedicine #Genomics #Bioengineering #SyntheticBiology
Want to get to know our new professor Charles Underwood? We interviewed him about his plans at @Radboud_uni :
"I want to address fundamental questions in reproduction biology, as a foundation for generating new biotechnologies useful in crop breeding."
https://www.ru.nl/en/about-us/news/interview-with-charles-underwood-new-professor-of-plant-genome-engineering
#plantgenome #genomeengineering #biotechnology #cropbiotechnology #reproductionbiology #biology #tomatoes #apomixis
In November 2023, Charles Underwood started working at the Radboud Institute of Biological and Environmental Sciences as a professor of Plant Genome Engineering. In this interview, you can read more about his research interests and plans.
📢#Engineering #plants for a changing climate📢
Given ongoing heatwaves, floods and other climate-change-related events @PLOSBiology's collection of commissioned Perspectives and Essays seems timely
It explores engineering strategies to help adapt plants to a changing climate & increase #CarbonCapture
Let us know what you think! @PLOSBiology welcomes related primary research
#climatechange #agriculture #bioengineering #microbiome #breeding #GenomeEngineering
https://collections.plos.org/collection/engineering-plants-for-a-changing-climate/
Today in #tucson it will be 114F/45C.
In related news, @PLOSBiology has published **Engineering plants for a changing climate**, that "explores engineering strategies to help us adapt plants to a changing climate, including breeding techniques, #GenomeEngineering , #SyntheticBiology and #microbiome engineering, with a focus on creating climate-resilient varieties and increasing the #CarbonCapture potential of croplands."
#climatechange
#agriculture
#bioengineering
https://collections.plos.org/collection/engineering-plants-for-a-changing-climate/
In a new paper out today in Nature Biotechnology, the Doudna lab develops #CRISPR-CSM for targeting RNA in human cells. Learn more: https://innovativegenomics.org/news/new-approach-rna-editing/
#GenomeEditing #GeneEditing #GenomeEngineering #innovation #research #berkeley #JenniferDoudna
Published today in Nature Biotechnology, a new paper from IGI postdoc David Colognori, IGI bioinformatician Marena Trinidad, and IGI Founder Jennifer Doudna develops the CRISPR-CSM system for use in human and other eukaryotic cells. CRISPR-CSM is a type III CRISPR system, which targets RNA for cutting and degradation. Unlike other RNA-targeting technologies, CRISPR-CSM can reach […]