How Alcoholic Drinks Cause Cancer: Boston's Dana-Farber clinicians explain. #alcohol #cancer #mutations #acetaldehyde #liver #breast #obesity
https://www.instagram.com/drhowardsmithreports/reel/DE2_4R0O5BN/
Howard G. Smith MD, AM on Instagram: "How Alcoholic Drinks Cause Cancer Even occasional drinkers raise their risk of cancer. From Boston’s famed Dana-Farber Cancer Institute come details on why that is true. Alcohol damages the tissues it touches all along your gastrointestinal tract creating oxidative stress in cells. When your cells try to repair themselves, DNA changes, that is mutations, occur and some lead to cancer. Then too, alcohol is metabolized in your body to the carcinogen acetaldehyde. Alcohol directly inflames and damages your liver leading to cancer. It triggers increases in your body’s estrogen levels. For women, that can facilitate breast cancer development and studies show 15% of these cancers are alcohol-related. Finally, alcohol is a carb and puts pounds on you, a known cancer risk. Dana-Farber nutritionists recommend reserving any drinking only for special occasions. That doesn’t mean TGIF. https://blog.dana-farber.org/insight/2023/09/what-you-should-know-about-alcohol-consumption-and-cancer-risk/ #alcohol #cancer #mutations #acetaldehyde #liver #breast #obesity"

0 likes, 0 comments - drhowardsmithreports on January 15, 2025: "How Alcoholic Drinks Cause Cancer Even occasional drinkers raise their risk of cancer. From Boston’s famed Dana-Farber Cancer Institute come details on why that is true. Alcohol damages the tissues it touches all along your gastrointestinal tract creating oxidative stress in cells. When your cells try to repair themselves, DNA changes, that is mutations, occur and some lead to cancer. Then too, alcohol is metabolized in your body to the carcinogen acetaldehyde. Alcohol directly inflames and damages your liver leading to cancer. It triggers increases in your body’s estrogen levels. For women, that can facilitate breast cancer development and studies show 15% of these cancers are alcohol-related. Finally, alcohol is a carb and puts pounds on you, a known cancer risk. Dana-Farber nutritionists recommend reserving any drinking only for special occasions. That doesn’t mean TGIF. https://blog.dana-farber.org/insight/2023/09/what-you-should-know-about-alcohol-consumption-and-cancer-risk/ #alcohol #cancer #mutations #acetaldehyde #liver #breast #obesity".

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@sumisu3

Acetaldehyde 😐 that is the bad guy for causing hangover 🙁 Coincidentally, I was checking this drawing in my previous paper…

#acetaldehyde #alcohol #beer

Congratulation to our @drexelmcbg students - Jasmine Peake PhD (graduated) and Kalisse Horne - also to John Gilligan and our lab mom Chiaki Noguchi for publishing a nice paper in Cell Cycle - officially printed 🎉 🥳 🤩

It’s about alcohol and its effects on esophagus cancer, but I still drink 🍺 😐 I should reduce my alcohol consumption 🤔

#Alcohol #Acetaldehyde #Beer #Cancer #Esophagus

https://www.tandfonline.com/doi/full/10.1080/15384101.2023.2261740

@wineworldnews
And nowhere is it said that it is acetaldehyde causing the headaches, not quercetin. Quercetin is just suspected of interfering with the liver's ability to metabolize acetaldehyde in some people.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527027/# #wine #headache #acetaldehyde #quercetin
Overview: How Is Alcohol Metabolized by the Body?

Alcohol is eliminated from the body by various metabolic mechanisms. The primary enzymes involved are aldehyde dehydrogenase (ALDH), alcohol dehydrogenase (ADH), cytochrome P450 (CYP2E1), and catalase. Variations in the genes for these enzymes have been ...

PubMed Central (PMC)

@mpschramm

We have published several research articles along this line. It is one of my research projects that is purely based on my personal interest😉

Because acetaldehyde damages DNA, people (especially individual with heterozygous for this allele) shouldn't be drinking a lot. But people with homozygous for this mutation are not able to drink alcohol at all, so they never become alcoholic, which seems to be a positive effect🤔

#Alcohol #ALDH2 #Acetaldehyde #Drinking #Metabolism #Genetics

Triple IPA - 11.5% alcohol 🤔

I like this bitterness and light citrus flavor. But I feel alcohol a lot, thinking about acetaldehyde, the primary metabolite of alcohol, although my enzyme (ALDH2) that detoxifies acetaldehyde has no mutation 😉
About half of East Asian people have a mutation in this enzyme. I am looking forward to seeing our kids’ genotypes 🤔

#Alcohol #Acetaldehyde #Metabolism #Science #Genetics #AcetaldehydeDehydrogenase #ALDH2

Structural information on the thermostable acetaldehyde dehydrogenase from S. tokodaii in the holo form provides clues to the mechanisms of substrate recognition and hyperthermostability in these enzymes #Thermostability #Acetaldehyde #Dehydrogenases https://doi.org/10.1107/S2053230X23004430
Crystal structure of thermostable acetaldehyde dehydrogenase from the hyperthermophilic archaeon Sulfolobus tokodaii

Thermostable acetaldehyde dehydrogenase from S. tokodaii was prepared and its crystal structure was determined.

Acta Crystallographica Section F
Vaping: High lead and nickel found in illegal vapes

Lab analysis finds vapes confiscated from teenagers at a school pose a potential risk to health.

BBC News
> .. at the end of 1959, #Chisso’s president publicly drank a glass of water from the Cyclator, without announcing that the wastewater from the #acetaldehyde plant, which contained mercury, was not being run through the #Cyclator. An eerily similar performance took place on March 24, 2011 when #TokyoGovernor #IshiharaShintarō drank a glass of tap water on national television to “prove” that it was safe from #RadioactiveContamination.
https://apjjf.org/2012/10/11/Timothy-S.-George/3715/article.html
#TimothyGeorge #MinamataDisease
Fukushima in Light of Minamata

Fukushima in Light of Minamata Timothy S. George Abstract: The mercury discharged into the sea by the Chisso factory in Minamata, and the radiation released by the Fukushima Daiichi nuclear power p

The Asia-Pacific Journal: Japan Focus