π¦ Could we outsmart antibiotic resistance by turning bacteria against themselves?
π Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
π CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
Understanding quorum sensing fundamentally reframes microscopic organisms not as solitary entities, but as highly social, coordinated societies. By intercepting these chemical lexicons, modern science can sustainably manage devastating human diseases, balance complex ecosystems.
#WhatIs #Microbiology #Biochemistry #BiomolecularBiology,
#EvolutionaryBiology #Oncology #Pharmaceutical #MarineBiology #QuorumSensing #sflorghttps://www.sflorg.com/2026/04/wi04152601.html
What Is: Quorum Sensing
The relentless scientific exploration of Quorum Sensing has precipitated a profound, irreversible paradigm shift across the disciplines of microbiolog
Microbial
#dysbiosis alters chemical cues in the oral
#microbiome, but how do commensals sense these? This study shows that
#Streptococcus salivarius detects dysbiosis metabolites & repurposes a peptide
#QuorumSensing receptor to drive antibacterial predation
@PLOSBiology https://plos.io/4rtVSbf
Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci
Microbial dysbiosis alters chemical cues in the oral microbiome, but how commensals sense these changes is unclear. This study shows that Streptococcus salivarius detects dysbiosis metabolites and repurposes a peptide quorum-sensing receptor to drive sustained antibacterial predation, revealing a new form of interspecies chemical communication.
The science of how fireflies stay in sync
Engineers have uncovered the mathematical rules fireflies follow to sync up their flashes.
https://s.faithcollapsing.com/tvptu#biology #biophysics #collective-motion #quorum-sensing #science #swarms
The science of how fireflies stay in sync
Engineers have uncovered the mathematical rules fireflies follow to sync up their flashes.
New publication: AHL quorum sensing regulates T6SS and volatiles production in
#rice root-colonizing
#Enterobacter asburiae AG129, by @PaolinaGarbeva and others.
#bacteria #quorumsensinghttps://doi.org/10.1093/femsec/fiaf120Wow, I hadn't realised Nigel Franks didn't publish about this until 2015. He'd been talking about it as long as I'd been at Bath (since 2002), probably longer. Gives me hope for some of my own
#cooperation work that's languishing.
IMO,
#quorumSensing explains a LOT.
www.nature.com/articles/sre...How ants use quorum sensing to...
How ants use quorum sensing to estimate the average quality of a fluctuating resource - Scientific Reports
We show that one of the advantages of quorum-based decision-making is an ability to estimate the average value of a resource that fluctuates in quality. By using a quorum threshold, namely the number of ants within a new nest site, to determine their choice, the ants are in effect voting with their feet. Our results show that such quorum sensing is compatible with homogenization theory such that the average value of a new nest site is determined by ants accumulating within it when the nest site is of high quality and leaving when it is poor. Hence, the ants can estimate a surprisingly accurate running average quality of a complex resource through the use of extraordinarily simple procedures.
Many bacteria use
#QuorumSensing to control genes based on population density. This Primer explores a
@PLOSBiology study showing that in P. aeruginosa, two QS circuits activate each other, enhancing robustness & explaining redundancy. Paper:
https://plos.io/3I7DhRG Primer:
https://plos.io/4niSZZdBacterial
#QuorumSensing is often assumed to follow a strict hierarchy. This study finds that
#Pseudomonas aeruginosa instead uses a reciprocal, cooperative system that enhances responsiveness to population density & environmental changes
@PLOSBiology https://plos.io/3I7DhRGWinzig klein, doch hochkomplex:
#Bakterien sind faszinierende Organismen. Mithilfe chemischer Signale - dem sogenannten
#QuorumSensing - koordinieren sie ihr Verhalten kommunizieren in Lebensgemeinschaften. Mehr bei
@scifri im Podcast.
https://www.sciencefriday.com/segments/bacteria-communication-bonnie-bassler/
How Do Bacteria Talk To Each Other?
Bacteria are not as simple as their reputation suggests. Understanding how they communicate may lead to better disease treatments for us humans.
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