How Private Equity Oversees the Ethics of Drug Research

Many drug trials are vetted by companies with ties to the drugmakers, raising concerns about conflicts of interest and patient safety.

The New York Times

This episode is chilling. But important information, nonetheless.

The human guinea pigs testing drugs for a living.

"Thousands of Canadians make a living volunteering to test out new drugs in clinical trials, even if those drugs can have dangerous, unpredictable side-effects. Habiba Nosheen explores the ethical questions about that work in her new documentary, Bodies for Rent."

Short episode from The Current, I hope you can hear it where you live.

https://www.cbc.ca/listen/live-radio/1-63-the-current/clip/16096640-the-human-guinea-pigs-testing-drugs-living

#EllieKPosts #drugTrials #drugs

The human ‘guinea pigs’ testing drugs for a living | The Current with Matt Galloway | Live Radio | CBC Listen

Thousands of Canadians make a living volunteering to test out new drugs in clinical trials, even if those drugs can have dangerous, unpredictable side-effects. Habiba Nosheen explores the ethical questions about that work in her new documentary, Bodies for Rent.

CBC Listen
In the past year, I've seen at least 3 - 4 Indian movies in different languages about foreign pharmaceutical corporations coming to India and doing dangerous drug trials on children (generally in orphanages) and/or poor people in a given area.

Is this just movie-makers following a trend? Or a political attempt to foster isolationism through (subtle) propaganda? Or based on a kernel of truth?

Anybody know?

#Movies #India #Tamil #Telugu #DrugTrials #PropagandaOrTruth
Akkoma

"As was done with the successful metformin randomized trial shown to prevent Long Covid, participants were recruited digitally and sent the medication (be it active or placebo) via the mail. This is the concept of the direct-to-participant digitized clinical trial, at scale, through smartphone apps and websites, that my colleagues (especially Steven Steinhubl) and I introduced several years ago"
https://erictopol.substack.com/p/long-covid-mitochondria-the-big-miss
--
#LongCovid #fda #nih #DrugTrials #recover #NEISvoid
Long Covid: Mitochondria, the Big Miss, and Hope

Ground Truths

#SpiderHead is a film from the Black Mirror school of screenwriting. It begins in a progressive correctional facility funded by drug trials. Experimental drugs auto-injected by remote control pods, only after explicit verbal consent from the subject. What could go wrong? It's dark, no question, but like Devs, it's a thoughtful psychological thriller played out in a near-future, sci fi scenario.

#movies #SciFi #BlackMirror #DrugTrials #MedicalEthics

Researchers report one drug more effective in treating wet age-related macular degeneration

Researchers say the drug aflibercept performed better in a clinical trial than bevacizumab in helping wean people off treatments for wet age-related macular degeneration

Medical News Today
Canada should review how deferiprone was approved, doctors say | The Star https://bit.ly/3ojRBMU #HealthCanada #DrugApproval #deferiprone #UHN #DrugTrials #cdnpoli @canadiangreens @cdnpoli
Drug approval under the microscope as two doctors allege Health Canada received flawed evidence about blood medication

Health Canada’s approval of deferiprone relied in part on data from Toronto hospital patients who received the medication before it was licensed.

thestar.com
FDA needs to build in more flexibility for rare disease clinical trials

It's time for @DrCaliff_FDA and the FDA to fundamentally reimagine how drugs for rare diseases are developed and remove needless obstacles that hinder clinical trials for them.

STAT