🧬 #Bioinformatics: In RNA sequencing of tissue samples, researchers measure how much #RNA from a gene is present in the sample as a whole. So-called #deconvolution methods then try to infer the cellular composition from these measurements. A team from Innsbruck and Munich has now developed “omnideconv” — an openly accessible framework that makes different methods comparable through systematic benchmarking.

👉 https://omnideconv.org/

📖 https://link.springer.com/article/10.1186/s13059-026-03955-w

#Genomics #openScience

🧬 #Bioinformatik: Bei der RNA-Sequenzierung von Gewebeproben misst man, wie viel #RNA eines Gens in der gesamten Probe vorkommt. Mit sogenannten #Deconvolution-Verfahren versucht man dann, aus den Messdaten die Zell-Zusammensetzung zu berechnen. Ein Team von Uni Innsbruck & TU München entwickelte jetzt „omnideconv“ – ein frei zugängliches Framework, das verschiedene dieser Verfahren mit einem Benchmarking vergleichbar macht.

👉 https://omnideconv.org/

📖 https://link.springer.com/article/10.1186/s13059-026-03955-w

#Genomik

Probably the best and most versatile Stitching Software currently available. Join our free online WEBINAR on Jan. 27th, and see for yourself all the solutions that we offer for problematic stitching.
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#vignettingcorrection #deconvolution #microscopy #lightsheet #organoids #huygens

My son, Ronan, who is double-majoring in #biochemistry and #physics, is working at Georgetown University in DC this summer, on a #cancer research internship. His work focuses on #cell-type #deconvolution in spatial #transcriptomics.

I know nothing about biology, but I am assisting him with deconvolution. My MathsTodon friends, have you any guidance to offer, either in mathematics or in biology?

Sometimes, #deconvolution is used by #CS folks to mitigate noise and distortion in an image, provided the characteristic function of the interference source can be measured (or modelled).

I wonder if #radar #EE folks have tried deconvolving the reflected signal with a measured (or modelled) topography of the operating area, so as to cure the ills caused by the ground clutter.

#DSP #DIP

Ok, this is amazing.

https://inv.nadeko.net/watch?v=xDLxFGXuPEc

YT - Captain Disillusion - CD / Blur

#Blur #DeBlur #Convolution #Gaussian #DeConvolution #Fourier

Improving resolution and reducing noise in #fluorescence #microscopy with ensured fidelity.

#deconvolution #multi_resolution

https://phys.org/news/2024-08-resolution-noise-fluorescence-microscopy-fidelity.html

'Linear Regression With Unmatched Data: A Deconvolution Perspective', by Mona Azadkia, Fadoua Balabdaoui.

http://jmlr.org/papers/v25/22-0930.html

#deconvolution #identifiability #estimator