Hauke Drechsler

@HD_sci
2 Followers
89 Following
29 Posts
Biochemist/Molecular Biologist doing research on the Cell Biology and Biophysics of the human cytoskeleton in a plant science institute - is interdisciplinarity still a thing... ?
📰 "The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton"
by 🔬 José Rivera Alvarez, Laure Asselin, Peggy Tilly, Roxane Benoit, Claire Batisse, Ludovic Richert, Julien Batisse, Bastien Morlet, Florian Levet, Noémie Schwaller, Yves Mély, Marc Ruff et al.
https://pubmed.ncbi.nlm.nih.gov/37418324/ #Kinesin
The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton - PubMed

Completion of neuronal migration is critical for brain development. Kif21b is a plus-end-directed kinesin motor protein that promotes intracellular transport and controls microtubule dynamics in neurons. Here we report a physiological function of Kif21b during radial migration of projection neurons …

PubMed
📰 "The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling"
by 🔬 Kira V Gromova, Edda Thies, Philipp C Janiesch, Felix P Lützenkirchen, Yipeng Zhu, Daniele Stajano, Céline D Dürst, Michaela Schweizer, Anja Konietzny, Marina Mikhaylova, Christine E Gee et al.
https://pubmed.ncbi.nlm.nih.gov/37418322/ #Microtubule #Kinesin
The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling - PubMed

Homeostatic synaptic plasticity adjusts the strength of synapses to restrain neuronal activity within a physiological range. Postsynaptic guanylate kinase-associated protein (GKAP) controls the bidirectional synaptic scaling of AMPA receptors (AMPARs); however, mechanisms by which chronic activity t …

PubMed
How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812
Did you now...? That multi-well plate lids stack and seal nicely so that they can be re-used to store (oily) microscope slides in between? You're welcome 😉 #don'twastewaste
Useful random knowledge: 🧑‍🔬 mineral oil for PCR works well in hydraulic bike brakes 🧑‍🔧. Your welcome!
Being a parent in post-corona #germany is: going to the Kindergarten on Monday to ask for the week's reduced opening and closure times. Throwing parents and especially women back to 70s as they become an apparent liability for employers without any functional and reliable child care. So how about enabling people to actually work full-time @RegierungBW instead of complaining about the lack of skilled workers?!

Hello all, just a reminder that there is a #PostDoc #Vacancy with @roylelab which is closing today!

It’s a 1.5 year post on intracellular transport vesicle movement and molecular characterisation. Shorter contract due to the current postholder relocating to another country. Very cool project which we are all really excited about. Possibility of extension. Take a look:

https://bit.ly/3jz0JLm

#CellBiology #Microscopy #MembraneTraffic

University of Warwick Job Search: Research Fellow (104138-0223)

University of Warwick Job Search: Research Fellow (104138-0223)

Recruiting two postdocs interested in molecular motors, microtubule organisation, live cell imaging, protein biochemistry, and/or single molecule biophysics #jobs #postdoc Apply here: https://tinyurl.com/4svc8cc9 Get in touch with any Qs. #kinesin #dynein
University of Warwick Job Search: Research Fellow in Biochemistry and Quantitative Cell Biology x2 (101445-0223)

University of Warwick Job Search: Research Fellow in Biochemistry and Quantitative Cell Biology x2 (101445-0223)

Structural insights into actin isoforms

https://doi.org/10.7554/eLife.82015

Structural insights into actin isoforms

eLife
RT @CarstenJanke
A great collaboration with with the Braun & Lansky lab! We are happy to announce our latest paper:
https://www.embopress.org/doi/full/10.15252/embj.2022112101