What are the effects of #centrosome amplification in #cancer? @basto_lab &co show that extra centrosomes prime #OvarianCancer cells for #apoptosis, acting in synergy with #chemotherapy to induce cell death, correlating with improved survival #PLOSBiology https://plos.io/4dbmpD7
Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy

What are the effects of centrosome amplification in cancer? This study shows that extra centrosomes prime ovarian cancer cells for apoptosis, acting in synergy with chemotherapy to induce cell death. High centrosome numbers correlate with improved treatment responses and longer survival.

📣 Just heard that the Cilia2024 conference is almost fully booked! 😊  

Hurry and grab the last on-site spots for the world's biggest cilia meeting in beautiful Dublin!

Last-minute industry sponsors are welcome!

Online participation in this hybrid meeting is, of course, not limited.

Webpage: https://cilia2024.ie/

#Cilia2024 #Ciliopathies #RareDisease #ADPKD #PCD #BBS #NPHP #Centrosome #Centriole #CellBiology #DevelopmentalBiology #Nephrology #Neurology #EMBO @cilia @cellbiology

Cilia2024

#Centrosome growth in Drosophila embryos is connected to nuclear division cycles and regulated by the cell-cycle oscillator, rather than by a limiting component as in worms

#RefereedPreprint c/o @ReviewCommons by Jordan Raff and coworkers

https://www.embopress.org/doi/full/10.1038/s44318-023-00022-z

⚠️End of play today ⚠️ is the deadline for submitting an abstract to be considered for a talk and/or poster for our inperson UK Cilia Network Fall Meeting https://forms.office.com/e/EtTDAeGaFY

🎇Great opportunity for #cilia & #centrosome students, postdocs & #newPIs to give a podium talk!🎇

Microsoft Forms

🚨UK #cilia & #centrosome community🚨- if YOU want to give a talk or poster at our 1st in-person UK Cilia Network meeting since COVID in Edinburgh Oct 6th 2023 🤲🤲 you NEED to send an abstract before end of play Monday Sept 4th here: https://forms.office.com/e/EtTDAeGaFY

Our keynote is the amazing Dagmar Wachten, with talks on how you can get involved from Ciliopathy Alliance & new #RareDiseaseNode CILIA-REN: Renal Ciliopathies National Network! We will also be electing new ECR reps & leadership team members.

Microsoft Forms

Hey #cilia & #centrosome peeps, registration is now open for our in-person 🎇 UK Cilia Network Fall meeting🎇 in Edinburgh Friday October 6th, 2023! Our keynote will be from Prof Dagmar Wachten (Bonn, DE) 'Shedding light on ciliary signaling and function'. Lots of talk slots and posters spots too- join us!

Please register: https://forms.office.com/e/EtTDAeGaFY. Deadline for talk and poster consideration is 04/09/2023 17:00.

 Boosts welcome!

Microsoft Forms

`The genetically induced parthenogenetic #Drosophila melanogaster eggs exhibit de novo #centrosome formation, fusion of the meiotic products, and the onset of development to generate predominantly triploid offspring. Thus, we demonstrate a genetic basis for sporadic facultative #parthenogenesis in an animal.`

https://www.cell.com/current-biology/fulltext/S0960-9822(23)00913-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982223009132%3Fshowall%3Dtrue

Our #MidweekMovie shows nuclear migration in the #Drosophila oocyte. Maëlys Loh, @FredBernard and Antoine Guichet discover that Kinesin-1 promotes #centrosome clustering leading to #nuclear migration.

📖 @Dev_journal: https://journals.biologists.com/dev/article/150/13/dev201728/322681/Kinesin-1-promotes-centrosome-clustering-and

Kinesin-1 promotes centrosome clustering and nuclear migration in the Drosophila oocyte

Highlighted Article: This study identifies a crucial role of Kinesin-1 in centrosome clustering required for nuclear positioning and migration in the Drosophila oocyte.

The Company of Biologists

Register now for the amazing hybrid centrosome conference in Istanbul, hosted by Elif Nur Firat-Karalar!

Sharing this announcement on the fediverse. Unsure if Elif has joined Mastodon yet…

Some of us might see this as the basal body meeting 😉

@cilia
#Centrosome2023
#cilia #centrosome #centriole #Embo #EmboWorkshop #Science #zilien #RareDisease #ScienceMastodon #Zentrosom #developmentalbiology #biology @nephrology #CellBiology #Ciliopathy