ISOGGJul 31, 2024

“RNASeq analyses suggest Y-chromosome gene expression differs between brain and blood tissues but does not differ significantly in cases, controls or specific haplogroups. Overall, we did not find any strong associations between Y-chromosome genetics and Parkinson's disease, suggesting the explanation for the increased prevalence in males may lie elsewhere.” #isogg #dna #YDNA #Parkinsons #haplogroups #geneadons

https://pubmed.ncbi.nlm.nih.gov/36387750/

Analysis of Y chromosome haplogroups in Parkinson's disease - PubMed

Parkinson's disease is a complex neurodegenerative disorder that is about 1.5 times more prevalent in males than females. Extensive work has been done to identify the genetic risk factors behind Parkinson's disease on autosomes and more recently on Chromosome X, but work remains to be done on the ma …

PubMed
SvenJun 12, 2024

And we have just discovered another new Y-DNA haplogroup R-FTD79893 that can be traced back in genealogic time to the area around Osnabruck, Lower Saxony.

Last names are Burlage, Stottmann, and Hollenkamp.

Origin is near Ankum, Lower Saxony.

See https://www.wikitree.com/wiki/Burlage-42 #YDNA #wikitree @wikitree

Herman (Burlage) Stottman (abt.1656-1698) | WikiTree FREE Family Tree

Is this your ancestor? Compare DNA and explore genealogy for Herman (Burlage) Stottman born abt. 1656 Ankum, Fürstenau, Osnabrück, Heiliges Römisches Reich died 1698 Ankum, Fürstenau, Osnabrück, Heiliges Römisches Reich including research + descendants + Y-chromosome DNA + more in the free family tree community.

Mark DarbyshireJun 8, 2024

A distant Derby cousin and I recently got our Big Y-700 results back. I'm hoping other cousins from the last few centuries to millennium will test too to refine the results, but for now – behold our haplogroup! https://discover.familytreedna.com/y-dna/I-FTF58625

#Genealogy #Ancestry #FamilyHistory #Genetics #DNA #YDNA #Haplogroup #FamilyTreeDNA

Welcome to FamilyTreeDNA Discover

Discover more about your paternal ancestry and join in on the research!

FamilyTreeDNA Discover
Kelly Wheaton 🦫💧🐸 🌻🌹May 22, 2024
#dna #GeneticGenealogy #YDNA #genealogy #Geneadons #Fgc22501 what ten years of research has done #humandiaspora https://wheatonwood.com/2024/05/22/the-journey-of-one-4000-year-old-celtic-y-snp-rfgc22501-ten-years-of-discovery/ #prague #bohemia
The Journey of one 4000 Year old Celtic Y-SNP RFGC22501: Ten Years of Discovery

Background To recap my first dive into Genetic Genealogy was giving my husband a Family Tree DNA Y37 kit for Valentine’s Day in 2011. It was purely out of frustration, as traditional genealog…

Wheaton Wood
Show threadMark DarbyshireMay 18, 2024

So I'm getting tantalisingly close, but still waiting for that crucial first estimate of when the ancestor I share with some Derbies in America was born.

I think we're close to some of the connections on paper, but it will be hard to get any closer. DNA is a nifty extra tool to see if I'm on the right track.

#Ancestry #Genealogy #FamilyHistory #DNATest #FamilyTreeDNA #YDNA

Mark DarbyshireMay 18, 2024

A while back I upgraded to the Big Y-700 test with FamilyTreeDNA. Problem is, it takes months for the DNA sequencing to be done, then weeks to get a broad haplogroup (most recent common ancestor a few thousand years ago), then a more precise haplogroup (more recent common ancestor), then a list of matches and an estimate of how many years ago the most recent common ancestor was born.

#Ancestry #Genealogy #FamilyHistory #DNATest #FamilyTreeDNA #YDNA

ISOGGApr 27, 2024
Interesting decade old study on #YDNA of #HouseofBourbon #isogg #whitathey #whitspredictor #dna #ydna #geneadons https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992573/
Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent identification of the presumed remains of two French Kings

Genetic analysis strongly increases the opportunity to identify skeletal remains or other biological samples from historical figures. However, validation of this identification is essential and should be done by DNA typing of living relatives. Based on ...

PubMed Central (PMC)
P. Y. Mund's GenealogyAug 14, 2023

A new 🧬 adventure begins. Y not? mito's well.

(I've had my autosomal DNA results transferred to FamilyTreeDNA for a while now, but I'd like to get the hang of Y-DNA and mtDNA matches, and with the recent sale, I decided: why not start with myself?)

#Genealogy #GeneticGenealogy #YDNA #mtDNA #FamilyTreeDNA

SvenAug 1, 2023
#familytreedna is nailing it this year for me! After the addition of the #yDNA Discovery tool and the new Globetrekker, yesterday, they also announced something for their autosomal DNA customers: a yDNA-haplogroup in the Metal Age https://blog.familytreedna.com/y-dna-haplogroups-family-finder/
Introducing Y-DNA Haplogroups for Family Finder Customers

This blog is about a new feature that will be added to Family Finder in the coming weeks. Customers with existing Family Finder results will receive an email announcement when the feature is released, as well as an email notification once their haplogroup has been added to their results.

FamilyTreeDNA Blog
ISOGGJul 30, 2023
“Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling the analysis of traditionally neglected chromosomes, such as the human Y chromosome (chrY).”#isogg #dna #geneadons #epigenetics #YDNA
https://www.nature.com/articles/s42003-023-05004-9
Y chromosome sequence and epigenomic reconstruction across human populations - Communications Biology

This study generates genome assemblies for seven major haplogroups of the human Y chromosome at a unique resolution that overcomes the structurally complex regions within. These data enable the detection and profiling of epigenetic modifications among the considered haplogroups.

Nature